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眼内注射头孢拉定与地塞米松治疗蜡样芽胞杆菌性全眼球炎实验观察
引用本文:姚亦群,陈钦元,汪素萍,周忆萍,刘国旌,施怡洁,郜岚. 眼内注射头孢拉定与地塞米松治疗蜡样芽胞杆菌性全眼球炎实验观察[J]. 眼科研究, 1991, 0(3)
作者姓名:姚亦群  陈钦元  汪素萍  周忆萍  刘国旌  施怡洁  郜岚
作者单位:上海医科大学附属眼耳鼻喉科医院 200031(姚亦群,陈钦元,汪素萍,周忆萍,刘国旌,施怡洁),上海医科大学附属眼耳鼻喉科医院 200031(郜岚)
摘    要:通过兔眼内注射头孢拉定与地塞米松,并应用ERG与病理检查,观察该药物的毒性作用和对蜡样芽胞杆菌引起的暴发性全眼球炎的治疗效果。结果头孢拉定25mg/ml,地塞米松400μg/ml作玻璃体腔注射无毒性。早期应用该药物有一定的抗菌作用。反复多次给药,在控制炎症方面效果为佳。

关 键 词:蜡样杆菌  全眼球炎  头孢拉定  玻璃体注射

Experimental Study of Intraocular Injection of Cephradine in the Treatment of Panophthalmitis Caused by Bacillus Cereus
Yao Yiqun,et al Eye , ENT Hospital,Shanghai Medical University,Shanghai. Experimental Study of Intraocular Injection of Cephradine in the Treatment of Panophthalmitis Caused by Bacillus Cereus[J]. Chinese Ophthalmic Research, 1991, 0(3)
Authors:Yao Yiqun  et al Eye & ENT Hospital  Shanghai Medical University  Shanghai
Abstract:So far there is no effective treatment in the sudden onset of panophthalmitis caused by Bacillus Cereus clinically. This study was to inject Cephradine and Dexamethasone intravitreously into the rabbit eye and observe the toxicity and the effect treatment in association with the ERG and pathological examination. The experiments showed that Cephradine 25mg/ml, Dexamethasone 400ug/0.1ml intravitreal injection had no toxic effect. Early application of these medicine had some anti-bacterium effect. Repeated use showed better results in controlling the inflammation than that of single dosage. This result might offer some references in the treatment of panophthalmitis clinically.
Keywords:acillus cereus  panophthalmitis  intravitreous injection  cephradine.
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