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Apyrase treatment prevents ischemia-reperfusion injury in rat lung isografts |
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| Authors: | Seiichiro Sugimoto Xue Lin Jiaming Lai Mikio Okazaki Nitin A. Das Wenjun Li Alexander S. Krupnick Ridong Chen Soon Seog Jeong G.A. Patterson Daniel Kreisel Andrew E. Gelman |
| Affiliation: | a Division of Cardiothoracic Surgery, Department of Surgery, Washington University School of Medicine, St Louis, Mo b APT Therapeutics Inc, St Louis, Mo |
| Abstract: | |
| Keywords: | ADP, adenosine diphosphate ATP, adenosine triphosphate BAL, bronchoalveolar lavage CD39, ectonucleoside triphosphate diphosphohydrolase-1 EBD, Evans blue dye EC, endothelial cell ELISA, enzyme-linked immunosorbent assay IgG, immunoglobulin G IL-1β, inteleukin-1β IRI, ischemia-reperfusion injury MIP-2, macrophage inflammatory protein-2 MPO, myeloperoxidase PBS, phosphate-buffered saline TNF-α, tumor necrosis factor-α TUNEL, terminal deoxynucleotidyl transferase dUTP nick end labeling |
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