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不同剂量的川芎唪对急性缺血性脑血管疾病的疗效观察
引用本文:蔡永亮 任明山. 不同剂量的川芎唪对急性缺血性脑血管疾病的疗效观察[J]. 中国中西医结合杂志, 2000, 20(10): 747-749
作者姓名:蔡永亮 任明山
作者单位:安徽中医学院神经病学研究所,合肥
摘    要:目的:探讨不同剂量的川芎嗪对急性缺血性脑血管疾病(ICVD)的临床疗效及血液流变学的影响。方法:69例ICVD患者随机分为A组(川芎嗪120mg)、B组(川芎嗪240mg)、C组(川芎嗪480mg)3组,观察3组患者治疗前后临床疗效、神经功能缺损评分及血液流变学指标的变化。结果:神经功能缺损评分:B组、C组与治疗前比较,差异有显著性;总有效率:A、C两组间比较,差异有显著性;血液流变学:与治疗前比

关 键 词:川芎嗪  急性缺血性脑血管疾病  中医药疗法
修稿时间:2000-01-03

Observation on Curative Effect of Acute Ischemic Cerebrovascular Disease Treated with Different Dosage of Ligustrazine
CAI Yongliang,REN Mingshan,YANG Renmin,et al.. Observation on Curative Effect of Acute Ischemic Cerebrovascular Disease Treated with Different Dosage of Ligustrazine[J]. Chinese journal of integrated traditional and Western medicine, 2000, 20(10): 747-749
Authors:CAI Yongliang  REN Mingshan  YANG Renmin  et al.
Abstract:Objective: To compare clinical curative effect of acute ischemic cerebrovascular diseases (ICVD) treated with different dosage of ligustrazine and to observe the effect of ligustrazine on hemorrheology. Methods: Sixty nine patients with ICVD were randomized into three groups, the Group A, B and C treated with 120mg, 240mg and 480mg of ligustrazine respectively, the clinical curative effect, the changes in nerve function deficit score and hemorrheologic parameters before and after treatment were observed. Results: The clinical curative effect and improvement of hemorrheologic parameters in Group C were better than those in Group A and B significantly (P<0 05,P<0 01 respectively). Ligustrazine also showed obvious effect in lowering blood level of fibrinogen in Group C. Conclusion: Treatment of acute ICVD with large dose of ligustrazine is good in improving clinical effect and hemorrheology, and without side effect basically.
Keywords:ligustrazine   acute ischemic cerebrovascular disease   hemorrheology
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