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Resection of a locally advanced hilar tumor and the hepatic artery after stepwise hepatic arterial embolization: A case report
作者姓名:Miura T  Hakamada K  Ohata T  Narumi S  Toyoki Y  Nara M  Ishido K  Ohashi M  Akasaka H  Jin H  Kubo N  Ono S  Kijima H  Sasaki M
作者单位:Takuya Miura(Department of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine, Hirosaki 036-8562, Japan) ; Kenichi Hakamada(Department of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine, Hirosaki 036-8562, Japan) ; Takashi Ohata(Department of Radiology and Radiation Oncology, Hirosaki University Graduate School of Medicine, Hirosaki 036-8562, Japan) ; Shunji Narumi(Department of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine, Hirosaki 036-8562, Japan) ; Yoshikazu Toyoki(Department of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine, Hirosaki 036-8562, Japan) ; Masaki Nara(Department of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine, Hirosaki 036-8562, Japan) ; Keinosuke Ishido(Department of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine, Hirosaki 036-8562, Japan) ; Motonari Ohashi(Department of Pathology and Bioscience, Hirosaki University Graduate School of Medicine, Hirosaki 036-8562, Japan) ; Harue Akasaka(Department of Pathology and Bioscience, Hirosaki University Graduate School of Medicine, Hirosaki 036-8562, Japan) ; Hiroyuki Jin(Department of Pathology and Bioscience, Hirosaki University Graduate School of Medicine, Hirosaki 036-8562, Japan) ; Norihito Kubo(Department of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine, Hirosaki 036-8562, Japan) ; Shuichi Ono(Department of Radiology and Radiation Oncology, Hirosaki University Graduate School of Medicine, Hirosaki 036-8562, Japan) ; Hiroshi Kijima(Department of Pathology and Bioscience, Hirosaki University Graduate School of Medicine, Hirosaki 036-8562, Japan) ; Mutsuo Sasaki(Department of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine, Hirosaki 036-8562, Japan) ;
摘    要:We herein report a case of a hilar tumor with extensive invasion to the proper hepatic artery, which was successfully treated with a radical resection in a 57-year-old female patient after a stepwise hepatic arterial embolization. She underwent right colectomy and partial hepatectomy for advanced colon cancer two years ago and radiofrequency ablation therapy for a liver metastasis one year ago, respectively. A recurrent tumor was noted around the proper hepatic artery with invasion to the left hepatic duct and right hepatic artery 7 mo previously. We planned a radical resection for the patient 5 mo after the absence of tumor progression was confirmed while he was undergoing chemotherapy. To avoid surgery-related liver failure, we tried to promote the formation of collateral hepatic arteries after stepwise arterial embolization of the posterior and anterior hepatic arteries two weeks apart. Finally, the proper hepatic artery was occluded after formation of collateral flow from the inferior phrenic and superior mesenteric arteries was confirmed. One month later, a left hepatectomy with hepatic arterial resection was successfully performed without any major complications.

关 键 词:肝动脉栓塞  门肿瘤  动脉切除术  间接动脉
收稿时间:2008 Feb 5

Resection of a locally advanced hilar tumor and the hepatic artery after stepwise hepatic arterial embolization: a case report
Miura T,Hakamada K,Ohata T,Narumi S,Toyoki Y,Nara M,Ishido K,Ohashi M,Akasaka H,Jin H,Kubo N,Ono S,Kijima H,Sasaki M.Resection of a locally advanced hilar tumor and the hepatic artery after stepwise hepatic arterial embolization: a case report[J].World Journal of Gastroenterology,2008,14(22):3587-3590.
Authors:Miura Takuya  Hakamada Kenichi  Ohata Takashi  Narumi Shunji  Toyoki Yoshikazu  Nara Masaki  Ishido Keinosuke  Ohashi Motonari  Akasaka Harue  Jin Hiroyuki  Kubo Norihito  Ono Shuichi  Kijima Hiroshi  Sasaki Mutsuo
Institution:1. Department of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine, Hirosaki 036-8562, Japan
2. Department of Radiology and Radiation Oncology, Hirosaki University Graduate School of Medicine, Hirosaki 036-8562, Japan
3. Department of Pathology and Bioscience, Hirosaki University Graduate School of Medicine, Hirosaki 036-8562, Japan
Abstract:We herein report a case of a hilar tumor with extensive invasion to the proper hepatic artery, which was successfully treated with a radical resection in a 57-year-old female patient after a stepwise hepatic arterial embolization. She underwent right colectomy and partial hepatectomy for advanced colon cancer two years ago and radiofrequency ablation therapy for a liver metastasis one year ago, respectively. A recurrent tumor was noted around the proper hepatic artery with invasion to the left hepatic duct and right hepatic artery 7 mo previously. We planned a radical resection for the patient 5 mo after the absence of tumor progression was confirmed while he was undergoing chemotherapy. To avoid surgery-related liver failure, we tried to promote the formation of collateral hepatic arteries after stepwise arterial embolization of the posterior and anterior hepatic arteries two weeks apart. Finally, the proper hepatic artery was occluded after formation of collateral flow from the inferior phrenic and superior mesenteric arteries was confirmed. One month later, a left hepatectomy with hepatic arterial resection was successfully performed without any major complications.
Keywords:Hepatic arterial embolization  Stepwise  Hilar tumor  Arterial resection  Collateral artery
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