Distribution de deux peptides de l'acide γ-aminobutyrique dans le liquide céphalo-rachidien et le cerveau humains |
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| Authors: | Nicole van Regemorter Y Hardens A Lowenthal M Van Sande F Lavinha |
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| Affiliation: | ∗ Département de Neurochimie, Fondation Born-Bunge, Berchem-Anvers, et Laboratoire de Chimie Médicale, BruxellesBelgique;∗∗ Institut de Pharmacie, Université Libre de Bruxelles, BruxellesBelgique |
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| Abstract: | The distribution of two peptides of γ-aminobutyric acid, homocarnosine and α-(γ-aminobutyryl)-lysine, was studied in human brain and cerebrospinal fluid. Adult brain and cerebrospinal fluid α- (γ-aminobutyryl) -lysine levels and adult brain homocarnosine levels are higher than those found in children. On the other hand, it is known that the cerebrospinal fluid from children contains higher concentrations of homocarnosine than those observed in adults. |
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| Keywords: | GABA, acide γ-aminobutyrique GABA-Lys, α-(γ-aminobutyryl)-lysine LCR, liquide cé phalo-rachidien |
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