| 选择素与急性胰腺炎 |
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| 引用本文： | 王存,周总光. 选择素与急性胰腺炎[J]. 中国普外基础与临床杂志, 2003, 10(3): 309-310,313 |
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| 作者姓名： | 王存 周总光 |
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| 作者单位： | 四川大学华西医院普外科,成都,610041 |
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| 基金项目： | 国家自然科学基金资助 (项目编号 :3992 50 32 ) |
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| 摘 要： | 目的 了解选择素在急性胰腺炎发病及病程进展中的作用，为进一步研究提供方向，指导临床治疗实践。方法 综述选择素在急性胰腺炎时的病理生理作用机理。结果 选择素水平在急性胰腺炎过程中古明显变化，并与细胞因子、氧自由基、补体等密切相关。结论 选择素是急性胰腺炎病理机理的组成部分，其表达水平对临床疾病的观察及治疗有指导意义。
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| 关 键 词： | 选择素 急性胰腺炎 治疗 病理生理作用 细胞因子 氧自由基 补体 |
| 文章编号： | 1007-9424(2003)03-0309-02 |
Selectin and Acute Pancreatitis |
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| WANG Cun,ZHOU Zong guang. Selectin and Acute Pancreatitis[J]. Chinese Journal of Bases and Clinics In General Surgery, 2003, 10(3): 309-310,313 |
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| Authors: | WANG Cun ZHOU Zong guang |
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| Affiliation: | WANG Cun,ZHOU Zong guang. Department of General Surgery,West China Hospital,Sichuan University,Chengdu 610041,China |
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| Abstract: | Objective To study the function of selectin in the pathogenesis and advancement of acute pancreatitis(AP), so as to guide further investigation and clinical treatment. Methods Correlative articles in recent years were reviewed. Results Selectins act as an indicator of the activation of endothelium. Their expression changes markedly during AP and is closely related to cytokines, oxygen free radicals and complements. Conclusion Selectin is a component which is engaged in the pathology of AP, the level of selectin is useful in guiding clinical observation and treatment. |
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| Keywords: | Acute pancreatitis Selectin [Foundation item] National Natural Science Foundation of China (No.39925032) |
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