Cyto-histologic correlation of crystal-storing histiocytosis: Rare presentation in breast,predating diagnosis of B-cell lymphoma by two years |
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| Affiliation: | 1. Evidence-Based Practice Center, Mayo Clinic, Rochester, USA;2. Department of Laboratory Medicine and pathology, Mayo Clinic, Rochester, USA;1. Department of Pathology, University of California San Diego, La Jolla, CA, United States of America;2. Health Sciences International, University of California San Diego, La Jolla, CA, United States of America;1. Department of Pathology, Ankara Training and Research Hospital, Ankara, Turkey;2. Department of Biomedical Engineering, TOBB University of Economics and Technology, Ankara, Turkey;3. Department of Medical Microbiology, Gulhane Institute of Health Sciences, Ankara, Turkey;4. Department of General Surgery, Gülhane Education and Research Hospital, Ankara, Turkey;1. N.N. Petrov Institute of Oncology, St.-Petersburg 197758, Russia;2. Moscow City Oncological Hospital №62, Moscow 143423, Russia;3. S. Berezin International Institute of Biological Systems, Saint-Petersburg 197758, Russia;4. St.-Petersburg Pediatric Medical University, St.-Petersburg 194100, Russia;5. I.I. Mechnikov North-Western Medical University, St.-Petersburg 191015, Russia;1. Chulabhorn International College of Medicine, Thammasat University, Pathumthani, Thailand;2. Division of Pathology, Thammasat University Hospital, Pathumthani, Thailand;3. Department of Pathology, King Chulalongkorn Memorial Hospital, Bangkok, Thailand |
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| Abstract: | Crystal-storing histiocytosis (CSH) is a rare disorder characterized by the accumulation of crystalized immunoglobulins within the cytoplasm of histiocytes. It is often associated with an underlying lymphoproliferative or plasma cell disorder. Most patients with CSH are asymptomatic in regard to the disease and are incidentally discovered. Herein we present cyto-histologic correlation of a rare example of CSH presenting with a two-year interval between original diagnosis of CSH and confirmation of a low-grade B-cell lymphoma. |
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