Effects of restoration of cough via spinal cord stimulation on subject quality of life |
| |
| Affiliation: | 1. Department of Physical Medicine and Rehabilitation, Case Western Reserve University, MetroHealth Medical Center, Cleveland, OH, USA;2. Department of Neurosurgery, Case Western Reserve University, MetroHealth Medical Center, Cleveland, OH, USA;3. Department of Research, Case Western Reserve University, MetroHealth Medical Center, Cleveland, OH, USA;4. Department of Physical Medicine and Rehabilitation, Cleveland Clinic, Cleveland, OH, USA;1. Department of Orthopedic Surgery and Traumatology, Sports Orthopedic Research Center Zuyderland, Dr. H. van der Hoffplein 1, 6162 BG, Sittard-Geleen, the Netherlands;2. Maastricht University, Faculty of Health Medicine & Life Sciences, Maastricht, the Netherlands;3. School of Care and Public Health Research Institute, Faculty of Health, Medicine & Life Sciences, Maastricht University Medical Center, Maastricht, the Netherlands;1. Department of Trauma & Orthopaedic Surgery, Queen Elizabeth Hospital Birmingham, UHB, Mindelsohn Way, Birmingham, B15 2GW, UK;2. Department of Radiology, Queen Elizabeth Hospital Birmingham, UHB, Mindelsohn Way, Birmingham, B15 2GW, UK;3. Department of Radiology, Royal Orthopaedic Hospital, Birmingham, Bristol Rd S, Northfield, Birmingham, B31 2AP, UK;1. Department of Orthopaedics and Joint Replacement Surgery, Indraprastha Apollo Hospitals, Sarita Vihar, New Delhi, 110 076, India;2. Formerly with CSIR-NISTADS, New Delhi, 110 012, India;3. Government First Grade College, Jagalur, 577528, Karnataka, India;1. Department of Orthopaedic Surgery, Ogori Daiichi General Hospital, Ogori Daiichi General Hospital, 839-1 Ogori-shimogo, Yamaguchi, 754-0002, Japan;2. Department of Orthopedic Surgery, Yamaguchi University Graduate School of Medicine, Ube, Japan;1. Department of Neurosurgery, Medical College of Wisconsin, Milwaukee, WI, USA;2. Division of Biostatistics, Medical College of Wisconsin, Milwaukee, WI, USA |
| |
| Abstract: | ObjectivesTo determine participant quality of life before and after use of the cough stimulation system (Cough System).DesignProspective assessment of life quality at 4 timepoints via questionnaire responses.SettingOut-patient hospital, United States.Participants28 subjects with spinal cord injury (SCI) completed life quality assessment questionnaires before and at the 28- 40- and 52-week timepoints following use of the Cough System.ResultsEach subject demonstrated significant clinical improvements in terms of restoration of an effective cough and ability to manage airway secretions with use of the Cough System. Positive airway pressures and peak expiratory airflows approached values associated with a normal cough. Related to cough/secretion management, use of this system also resulted less interference with family life and daily activities, less financial difficulties, less requirement for caregiver assistance, less stress, less embarrassment and greater control of their breathing problems (p < 0.01), for each comparison). There also significant improvements in that their overall health and quality of life (p < 0.01, for each comparison). Subjects also reported greater ease in breathing, restored ability to sneeze and enhanced mobility. The incidence of acute respiratory tract infections fell from 1.3 ± 0.3 to 0.2 ± 0.1 events/subject year (p < 0.01). Ten subjects developed mild hemodynamic effects consistent with autonomic dysreflexia that abated completely with continued use of the Cough System. Some subjects experienced mild leg jerks during SCS, which were well tolerated and abated completely with reduction in stimulus amplitude, No subjects reported bowel or bladder leakage.ConclusionUse of the Cough System by SCI subjects is a safe and efficacious method which significantly improves life quality and has the potential to reduce the mortality and morbidity associated with SCI. |
| |
| Keywords: | Spinal cord injury Spinal cord stimulation Cough Rehabilitation Quality of life |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
