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"When and how are peritoneal metastases of colo-rectal origin treatable"
Affiliation:1. Surgical Oncology and General Surgery Department, King Khaled Hospital, Najran, Saudi Arabia;1. Department of Thoracic Surgery, National Hospital Organization Yamaguchi Ube Medical Center, 685 Higashikiwa Ube, Yamaguchi, 755-0241, Japan;2. Clinical Research, National Hospital Organization Yamaguchi Ube Medical Center, 685 Higashikiwa Ube, Yamaguchi, 755-0241, Japan;3. Department of Pathology, KYURIN/ KYURIN PACELL Corporation, 26-67 Morishita-cho, Yahatanishi-ku, Kitakyushu, Fukuoka, 806-0046, Japan;4. Department of Pathology, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami-Kogushi, Ube, Yamaguchi, 755-8505, Japan;1. Department of Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, South Korea;1. University of Cologne, Faculty of Medicine and University Hospital Cologne, Department of Cardiothoracic Surgery, Kerpener Strasse 62, 50937, Cologne, Germany;2. University of Cologne, Faculty of Medicine and University Hospital Cologne, Institute for Pathology, Kerpener Strasse 62, 50937, Cologne, Germany;3. University of Cologne, Faculty of Medicine, Joseph-Stelzmann-Strasse 20, 50931, Köln, Germany;1. Department of Clinical Medicine and Surgery, Division of Minimally Invasive and Robotic HPB Surgery, “Federico II” University, Naples, Italy;2. Department of Digestive Surgery and Liver Transplantation, University of Montpellier, France;3. Department of Surgical Oncology, Institut du Cancer de Montpellier - ICM, University of Montpellier, Montpellier, France;4. General and Emergency Surgery Unit, GB Grassi Hospital, Rome, Italy;5. Department of Radiology, Montpellier University Hospital, France
Abstract:Peritoneal metastasis (PM) of colorectal cancer (CRC) origin can be treated and cured. This article presents a practical guide for CRC surgeons facing a patient with PM and presents the different options of treatment at expert centers on peritoneal surface malignancies.The unexpected finding of PM could be overwhelming, especially during an emergency CRC surgery. Clear indications on managing these situations call for clarification to avoid any negative impact on the oncologic outcome of patients with CRC.All patients with PM of CRC origin must be evaluated by a tumor board or multidisciplinary team specialized in the management of peritoneal surface malignancies since currently there are available options of treatment for patients with resectable peritoneal disease, unresectable peritoneal disease, and even patients with synchronous liver metastases (LM) could benefit from a multimodal approach.
Keywords:Colorectal cancer  Peritoneal metastasis  HIPEC  PIPAC  PM"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  pc_mWtZ7COAOq"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  peritoneal metastases  CRC"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  pc_GrZeBZDQk3"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  colorectal cancer  LM"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  pc_d9vnHQ6gLD"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  liver metastases  HIPEC"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  pc_SThNOIfuLQ"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  hypertehrmic intraperitoneal chemotherapy  PIPAC"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  pc_WTGGbIKxFu"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  pressurized intraperitoneal aerosol chemotherapy  PCI"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  pc_JIIF3gGJ1s"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  peritoneal cancer index  CRS"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  pc_JJD75sGEZp"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  cytoreductive surgery  SC"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  pc_HeO8jf7OnB"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  systemich chemotherapy
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