PET-CT staging affects time to treatment in sarcoma |
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| Affiliation: | 1. Department of Orthopedic Surgery, Section of Orthopedic Oncology, Rush University Medical Center, Chicago, IL, USA;2. Department of Internal Medicine, Division of Hematology, Oncology and Cell Therapy, Rush University Medical Center, Chicago, IL, USA;1. Barzilai University Medical Center, Ashkelon, Israels;2. Faculty of Health Sciences, Ben-Gurion University of Negev, Beer-Sheva, Israel;3. Kaplan Medical Center, Hebrew University, Rehovot, Israel;4. Rabin Medical Center, Sackler School of Medicine, Tel Aviv University, Petah Tikva, Israel;5. Soroka Medical Center, Ben Gurion University of the Negev, Beer-Sheva, Israel;6. Assaf Haroffe Medical Center, Sackler School of Medicine, Tel Aviv University, Zrifin, Israel;7. Shaare Zedek Medical Center, Hebrew University, Jerusalem, Israel;8. Meir Medical Center, Sackler School of Medicine, Tel Aviv University, Kfar Saba, Israel;9. Hillel Yaffe Medical Center, Rappaport Faculty of Medicine, Technion, Hedera, Israel;10. Wolfson Medical Center, Holon, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel;11. Hadassah Medical Center, Hebrew University, Jerusalem, Israel;12. Ziv Medical Center, Bar Ilan University, Zfat, Israel;13. Carmel Medical Center, Rappaport Faculty of Medicine, Technion, Haifa, Israel;1. Department of Head and Neck Surgery, Chris O''Brien Lifehouse, Camperdown, Sydney, NSW, Australia;2. Central Clinical School, Faculty of Medicine and Health, the University of Sydney, Sydney, NSW, Australia;3. Faculty of Medicine, University of New South Wales, Randwick, Sydney, NSW, Australia;4. Royal Prince Alfred Institute of Academic Surgery, Sydney Local Health District, Sydney, Australia;5. Department of Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, NSW Health Pathology, Camperdown, Sydney, NSW, Australia;1. Department of Orthopaedic Surgery, The Johns Hopkins University School of Medicine, 601 North Caroline Street, Baltimore, MD, 21287, USA;2. Department of Oncology, The Johns Hopkins University School of Medicine, 401 North Broadway, Baltimore, MD, 21287, USA;1. University of Cologne, Faculty of Medicine and University Hospital Cologne, Department of Cardiothoracic Surgery, Kerpener Strasse 62, 50937, Cologne, Germany;2. University of Cologne, Faculty of Medicine and University Hospital Cologne, Institute for Pathology, Kerpener Strasse 62, 50937, Cologne, Germany;3. University of Cologne, Faculty of Medicine, Joseph-Stelzmann-Strasse 20, 50931, Köln, Germany;1. Surgical Oncology Program, Center for Cancer Research, National Cancer Institute, Bethesda, MD;2. Department of Surgery, Harbor UCLA Medical Center, Torrance, CA;3. SSM Health Saint Louis University Hospital, St. Louis, MO;1. Service ORL, chirurgie cervico-maxillo-faciale et audiophonologie, CHU de Poitiers, 86000 Poitiers, France;2. Service d’ORL, d’otoneurochirurgie et de chirurgie cervico-faciale, hospices civils de Lyon, centre hospitalier Lyon Sud, 69310 Pierre-Bénite cedex, France;3. Université de Lyon, université Lyon 1, 69003 Lyon, France;4. Service d’endocrinologie, CHU de Poitiers, 86000 Poitiers, France;5. Service d’anatomie et de cytologie pathologiques, CHU de Poitiers, 86000 Poitiers, France |
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| Abstract: | Background and objectivesPET-CTs are being increasingly utilized in sarcoma care. This study sought to investigate the impact of PET-CT acquisition on time to treatment initiation.MethodsThe records of bone and soft tissue sarcoma patients treated at our institution were reviewed. Dates of initial presentation to a sarcoma-treating physician and dates of treatment initiation were recorded.ResultsTime to treatment was greater in patients (p < 0.001) with median time to treatment of 26 days (IQR 17, 36) and 20 days (IQR 12, 29) for those who did and did not undergo PET-CT, respectively. Those who underwent PET-CT in addition to a plain chest CT also had significantly increased time to treatment (p < 0.001) with median time to treatment of 27 days (IQR 17, 36) and 20 days (IQR 13, 28) for those who underwent both studies and those who underwent plain CT alone, respectively.ConclusionsDespite a statistically significant increase in time to treatment with the acquisition of a PET-CT scan, the added time is likely clinically insignificant. Additionally, PET-CT may offer additional benefits in potentially more accurate staging. |
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| Keywords: | PET-CT Staging Surveillance Soft tissue sarcoma Bone sarcoma |
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