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黄芪对寻常型银屑病患者IL-6、IL-8及IL-10血浆水平的影响
引用本文:史立宏,李晓民,张秀荣,毛淑梅,康白.黄芪对寻常型银屑病患者IL-6、IL-8及IL-10血浆水平的影响[J].中国实用医药,2008,3(7):31-32.
作者姓名:史立宏  李晓民  张秀荣  毛淑梅  康白
作者单位:1. 山东省潍坊医学院药理学教研室,261042
2. 潍坊市皮肤病医院
摘    要:目的研究黄芪对进展期寻常型银屑病患者血浆IL-6、IL-8与IL-10水平的影响。方法采用放射免疫法检测57例进展期寻常型银屑病患者用黄芪治疗前后血浆IL-6、IL-8与IL-10水平的变化。结果黄芪能降低血浆中过高的IL-6、IL-8水平(P<0.01),升高IL-10水平(P<0.05)。结论黄芪能通过调节细胞因子与淋巴细胞功能而治疗银屑病。

关 键 词:银屑病  黄芪  白细胞介素(IL)

The effects of astragalus membranaceus on plasma interleukin-6 interleukin-8 and interleukin-10 of Psoriasis Vulgaris at progressive stage
SHI Li-hong,LI Xiao-min, ZHANG Xiu-rong, etal..The effects of astragalus membranaceus on plasma interleukin-6 interleukin-8 and interleukin-10 of Psoriasis Vulgaris at progressive stage[J].China Practical Medical,2008,3(7):31-32.
Authors:SHI Li-hong  LI Xiao-min  ZHANG Xiu-rong  etal
Abstract:Objective To investigate the effect of astragalus membranaceus on plasma levels of interleukin-6,interleukin-8 and interleukin-10 in patients with Psoriasis Vulgaris at progressive stage.MethodsBlood samples were taken before and after treatment with astragalus membranaceus,and the plasma levels of IL-6,IL-8 and IL-10 in 57 psoriatic patients were measured by ELISA.ResultsAstragalus membranaceus has the actions of reducing plasma levels of IL-6,IL-8 and elevating the level of IL-10 in progressiving Psoriasis Vulgaris.ConclusionAstragalus membranaceus can treat Psoriasis Vulgaris by targeting at the cytokines and modulating lymphocytic function.
Keywords:Psoriasis  Astragalus membranaceus  Interleukin
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