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| 老龄大鼠海马CA3区神经元锥体细胞超微结构变化 | |
| 引用本文： | 贺晓舟,杨秋佳,窦肇华,王伟,徐冶,王英姿.老龄大鼠海马CA3区神经元锥体细胞超微结构变化[J].吉林医药学院学报,2001,23(2):63-64. |
| 作者姓名： | 贺晓舟 杨秋佳 窦肇华 王伟 徐冶 王英姿 |
| 作者单位： | 1. 吉林军医学院组织胚胎学教研室, 2. 吉林军医学院病理学教研室, 3. 吉林军医学院人体解剖学教研室, 4. 吉林市市政设施管理处卫生所, |
| 摘 要： | 目的 观察老龄大鼠海马CA3区神经元锥体细胞的超微结构变化。方法 将Wistar大鼠分为老龄组和成年组 ,应用透射电镜观察海马CA3区锥体细胞超微结构。结果 老龄组CA3区锥体细胞出现核膜内陷、核仁体积减少 ,线粒体肿胀、变性等形态学改变。结论 大鼠在衰老过程中 ,海马CA3区锥体细胞超微结构出现退行性改变 |
| 关 键 词： | 海马 锥体细胞 超微结构 |
| 文章编号： | 1009-8488(2001)02-0063-02 |
| 修稿时间： | 2001年3月7日 |
Study on Ultrastructural Change of Neuronal Pyramidal Cells in Hippocampus CA3 Area of the Aged Rats |
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| HE Xiao-zhou,YANG Qiu-Jia,DOU Zhao-Hua,WANG Wei,XU Ye,WANG Ying-Zi.Study on Ultrastructural Change of Neuronal Pyramidal Cells in Hippocampus CA3 Area of the Aged Rats[J].Journal of Jilin Medical College,2001,23(2):63-64. | |
| Authors: | HE Xiao-zhou YANG Qiu-Jia DOU Zhao-Hua WANG Wei XU Ye WANG Ying-Zi |
| Institution: | HE Xiao Zhou 1,YANG Qiu Jia 2,DOU Zhao Hua 1,WANG Wei 3,XU Ye 1,WANG Ying Zi 4 |
| Abstract: | Objective To observe the ultrastructural change of neuronal pyramidal cells in hippocampus CA3 area of aged rats.Methods Wistar rats were divided into 2 groups:the control group and the test group and the ultrastructure of neuronal pyramidal cells in hippocampus CA3 area was observed with JEM 1200 EX TEM.Results Morphological changes such as nuclear membrane invagination,reduction of nucleolar volume,mitochondrial swelling and degeneration occurred to neuronal pyramidal cells in hippocampus CA3 area.Conclusion Retorgrade may appear in the ultrastructure of neuronal pyramidal cells in hippocampus CA3 area with rat senility. |
| Keywords: | hippocampus pyramidal cell ultrastructure |
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