| 冠心病患者红细胞变形能力与血浆脂质关系的研究及临床意义 |
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| 引用本文： | 葛智平 文宗曜. 冠心病患者红细胞变形能力与血浆脂质关系的研究及临床意义[J]. 中国心血管杂志, 1998, 3(6): 417-419 |
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| 作者姓名： | 葛智平 文宗曜 |
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| 作者单位： | 北京医科大学第三临床医学院内科，北京医科大学第三临床医学院内科，北京医科大学第三临床医学院内科，北京医科大学基础医学院血液流变学研究中心 北京100083，北京100083，北京100083 |
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| 摘 要： | 对30例经选择性冠状动脉造影术确诊为冠心病(CHD)的患者进行了红细胞变形能力(ED)的测定,并作了其与血浆脂蛋白(a)[Lp(a)]、总胆固醇(TC)及甘油三酯(TG)的相关性分析.结果显示:CHD组患者的ED明显低于对照组[红细胞变形指数(DI_(max)):P<0.001,,红细胞膜变形指数(IDI):P<0.005],IDI与血浆Lp(a)及TC呈负相关.提示:ED的变化可以作为CHD患者的一个临床参考指标,并对CHD的预防及治疗有指导意义.
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| 关 键 词： | 冠心病 红细胞变形能力 |
A study on correlation between erythrocyte deformability and lipid in patients with coronary heart disease and its clinical significance |
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| Ge Zhiping,Guo Jingxuan,Tan xiujuan,et al.. A study on correlation between erythrocyte deformability and lipid in patients with coronary heart disease and its clinical significance[J]. Chinese Journal of Cardiovascular Medicine, 1998, 3(6): 417-419 |
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| Authors: | Ge Zhiping Guo Jingxuan Tan xiujuan et al. |
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| Affiliation: | Ge Zhiping,Guo Jingxuan,Tan xiujuan,et al. Department of Cardiology,Third Hospital of Beijing Medical University,Beijing 100083 |
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| Abstract: | Erythrocyte deformability(ED) was measured in 30 patients with coronary athrosclerostic heart disease proved by coronary angiography and in 30 normal controls, analized correlation to lipoprotein(a) [Lp(a) ] , total cholesterol(TC) and triglyceride (TG) in plasma. ED was significantly lower in CHD than in controls [Deformation Index max (DImax ): p<0.001, Integration Deformation Index(IDI) :P< 0.005) , IDI was negatively correlated to Lp(a)and TC in plasma.The facts suggest ED be served as a clinical reference index and indicate prophylaxis and treatment of CHD significantly. |
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| Keywords: | coronary hert disease erythrocyte deformability |
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