| 心肌组织肾素-血管紧张素系统与心肌超微结构改变的研究 |
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| 引用本文： | 吴志峰,祝善俊.心肌组织肾素-血管紧张素系统与心肌超微结构改变的研究[J].中国心血管杂志,1998,3(2):89-91. |
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| 作者姓名： | 吴志峰 祝善俊 |
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| 作者单位： | 第三军医大学新桥医院 重庆400037
(吴志峰，祝善俊)，第三军医大学新桥医院 重庆400037(赵立平) |
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| 基金项目： | 国家自然科学基金资助课题 |
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| 摘 要： | 观察19例心功能障碍患者心脏局部肾素-血管紧张素系统(RAS),心功能及心肌超微结构的变化.结果显示心肌血管紧张素Ⅱ含量增高,与心脏指数呈显著负相关,与心肌超微结构改变呈显著正相关,提示心脏局部RAS活性增高对心功能和心肌结构变化的影响较为突出.
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| 关 键 词： | 心力衰竭 血管紧张素Ⅱ 心肌超微结构 |
A study on changes of Cardiac tissue Renin-angiotensin system and Myocardial ultramicro struc- ture in chronic heart failure. |
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| Wu Zhifeng,Zhu shanjun,Zhao Liping et al. Departnent of Cardiology. Xin Qiao Hospital,The Third Military Medical College. Chongqing.A study on changes of Cardiac tissue Renin-angiotensin system and Myocardial ultramicro struc- ture in chronic heart failure.[J].Chinese Journal of Cardiovascular Medicine,1998,3(2):89-91. |
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| Authors: | Wu Zhifeng Zhu shanjun Zhao Liping Departnent of Cardiology Xin Qiao Hospital The Third Military Medical College Chongqing |
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| Abstract: | We investigated the changes of cardiac local renin-angiotensin system, cardiac funtion and myocardial ultramicrostructure in 19 patients with chronic rhumatic valvular disease. The content of angiotensin Ⅱ in left ventricular myocardium was increased and negtively correlated with the cardiac index, but positively correlated with the grade of myocdial pathological changes. We concluded that increased activities of cardiac local renin-angiotensin system be unbeneficial for heart and aggravate the lesion of myocardial ultramicrostructure. |
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| Keywords: | heart failure renin-angiotensin system myocardial ultramicrostructure |
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