Influence of tetrahydrocannabinols (delta8-THC and delta9-THC) on body weight, food, and water intake in rats |
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| Authors: | Per-Olow Sjödén Torbjörn U.C. Järbe Bengt G. Henriksson |
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| Affiliation: | Neurophysiological Laboratory, Ulleråker Hospital, University of Uppsala, Uppsala, Sweden;Department of Psychology, University of Uppsala, Uppsala, Sweden |
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| Abstract: | Female Wistar rats, six to a group, were injected daily for a 23-day period with Δ8-THC (5.0 mg/kg), Δ9-THC (2.5 mg/kg) or vehicle. Body weight, food and water intake were recorded every second day. It was found that Δ8-THC caused a decrease of body weight, to a level maintained throughout the injection period, with only slight signs of recovery. Both drugs caused a marked decrease of water intake. Food intake was not significantly affected by the drugs. Factors in relation to the effects of THC on body weight, food and water intake are discussed. |
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| Keywords: | Body weight Food and water intake |
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