碳酸氢钠、双氧水、制霉菌素联合治疗义齿性口炎的探讨

目的探讨碳酸氢钠、双氧水、制霉菌素联合治疗义齿性口炎的疗效,为义齿性口炎患者提供一种简便易行的治疗方法。方法将56例义齿性口炎患者随机分成两组,对照组28人采用传统方法,以碳酸氢钠漱口,3次/d,睡前摘掉义齿,置于清水中浸泡;实验组28人以碳酸氢钠漱口,3次/d,义齿上涂抹制霉菌素,戴上义齿,睡前摘掉义齿,浸于双氧水中。于15d、30d观察治疗效果。结果治疗15d,实验组治愈率71.43%,高于对照组的35.71%（χ2=7.18,P〈0.01）,治疗30d,实验组治愈率89.29%,高于对照组的57.14%（χ2=7.38,P〈0.01）。结论使用碳酸氢钠、双氧水、制霉菌素联合治疗义齿性口炎,简单易行,较传统方法能明显提高治愈率。

Complex application of sodium bicarbonate hydrogen peroxide and nystatin in denture stomatitis therapy

Objective To survey the complex application of sodium bicarbonate hydrogen peroxide and nystatin in denture stomatitis therapy and provide a feasible method in denture stomatitis therapy.Methods 56 cases of denture stomatitis patients were separated into two groups randomly,group control 28 cases,gargle with sodium bicarbonate solution three times a day,take off denture before sleep,dip in clean water;experimental group 28 cases,gargle with sodium bicarbonate solution three times a day,smear nystatin on denture surface,put on dentures,take off denture before sleep and dip it in hydrogen peroxide,compare therapy effect after 15 and 30 days.Results After 15 days therapy effect was group control 35.71%,experimental group 71.43%(χ2=7.18,P <0.01),after 30 days of therapy group control 57.14%,experimental group 89.29%,effect rate of experimental group was significantly higher than group control(χ2=7.38,P <0.01).Conclusion Complex therapy with sodium bicarbonate hydrogen peroxide and nystatin may cure denture stomatitis effectively.