首页 | 本学科首页   官方微博 | 高级检索  
     


Bacterial Infection in Cirrhosis, with and without Hepatocellular Carcinoma
Authors:Hiroshi Yoshida  M.D.    Takaomi Hamada  M.D.    Sadataka Inuzuka  M.D.    Takato Ueno  M.D.    Michio Sata  M.D.   Kyuichi Tanikawa  M.D.
Affiliation:Second Department of Medicine Kurume University School of Medicine Kurume, Japan
Abstract:Objective: The extent and type of bacterial infection occurring with liver cirrhosis has remained unknown. Further, while hepatocellular carcinoma (HCC) is known to occur mainly in patients with liver cirrhosis, no report has yet investigated the incidence of bacterial infection in HCC. The purpose of the present study was to establish the prevalence of bacterial infection in patients with HCC. Methods : We have retrospectively investigated all 1140 patients with hepatic cirrhosis and/or HCC for any incidence of bacterial infection. Results : The incidence of bacterial infection was found to be 15.4%. in 740 patients with HCC. This was approximately equal to the incidence of bacterial infection in 400 patients with cirrhosis without HCC, which was found to be 15.3%. When the severity of cirrhosis was graded according to Child-Pugh classification, the incidences of bacterial infection in Child-Pugh class A. class B, and class C were 3.3%, 11.1%, and 31.2%, respectively, in cirrhosis, and 2.3%, 9.1%, and 25.6% in HCC The incidence of bacterial infection increased with the severitv of cirrhosis and severe bacterial infections occurred in Child-Pugh class B and C patients. Conclusion : The data suggest that the susceptibility of HCC patients to bacterial infection is mainly related to the underlying cirrhosis and not to the HCC.
Keywords:
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号