Ethanol drinking by rhesus monkeys as a function of concentration |
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Authors: | Jack E. Henningfield Richard A. Meisch |
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Affiliation: | (1) Psychiatry Research Unit, University of Minnesota, Mayo Box 392, 55455 Minneapolis, Minnesota, USA |
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Abstract: | Ethanol deliveries maintained fixed-ratio (FR) responding of three rhesus monkeys during daily 3-h sessions. At FR values of 8 or 16, ethanol concentration was varied in the sequence 0 (water), 8, 11.3, 16, 22.6, 32, 8, and 0% (w/v). As the ethanol concentration increased, number of liquid deliveries decreased, although intake of ethanol (g/kg/session) increased somewhat. Blood ethanol levels were usually greater than 200 mg% and occasionally greater than 300 mg%.These data were reported to the Committee on Problems of Drug Dependence (1976) and were part of a doctoral dissertation by J. E. Henningfield |
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Keywords: | Rhesus monkeys Ethanol reinforcement Ethanol concentration Blood ethanol level Ethanol drinking Fixed-ratio schedules Intoxication |
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