Tensile properties of commonly used prolapse meshes |
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Authors: | Keisha A Jones Andrew Feola Leslie Meyn Steven D Abramowitch Pamela A Moalli |
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Institution: | (1) Magee-Womens Research Institute, Division of Female Pelvic Medicine and Reconstructive Surgery, Department of Obstetrics &; Gynecology and Reproductive Sciences at Magee-Womens Hospital, University of Pittsburgh, Pittsburgh, PA 15213, USA;(2) Department of Bioengineering, Musculoskeletal Research Center, University of Pittsburgh, Pittsburgh, PA 15213, USA;(3) Division of Urogynecology Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh, 300 Halket Street, Pittsburgh, PA 15213, USA; |
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Abstract: | Introduction and hypothesis To improve our understanding of the differences in commonly used synthetic prolapse meshes, we compared four newer generation
meshes to Gynecare PS™ using a tensile testing protocol. We hypothesize that the newer meshes have inferior biomechanical
properties.
Methods Meshes were loaded to failure (n = 5 per group) generating load–elongation curves from which the stiffness, the load at failure, and the relative elongation
were determined. Additional mesh samples (n = 3) underwent a cyclic loading protocol to measure permanent elongation in response to subfailure loading.
Results With the exception of Popmesh, which displayed uniform stiffness, other meshes were characterized by a bilinear behavior.
Newer meshes were 70–90% less stiff than Gynecare™ (p < 0.05) and more readily deformed in response to uniaxial and cyclical loading (p < 0.001).
Conclusion Relative to Gynecare™, the newer generation of prolapse meshes were significantly less stiff, with irreversible deformation
at significantly lower loads. |
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Keywords: | Mesh Polypropylene Prolapse |
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