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Tensile properties of commonly used prolapse meshes
Authors:Keisha A Jones  Andrew Feola  Leslie Meyn  Steven D Abramowitch  Pamela A Moalli
Institution:(1) Magee-Womens Research Institute, Division of Female Pelvic Medicine and Reconstructive Surgery, Department of Obstetrics &; Gynecology and Reproductive Sciences at Magee-Womens Hospital, University of Pittsburgh, Pittsburgh, PA 15213, USA;(2) Department of Bioengineering, Musculoskeletal Research Center, University of Pittsburgh, Pittsburgh, PA 15213, USA;(3) Division of Urogynecology Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh, 300 Halket Street, Pittsburgh, PA 15213, USA;
Abstract:Introduction and hypothesis  To improve our understanding of the differences in commonly used synthetic prolapse meshes, we compared four newer generation meshes to Gynecare PS™ using a tensile testing protocol. We hypothesize that the newer meshes have inferior biomechanical properties. Methods  Meshes were loaded to failure (n = 5 per group) generating load–elongation curves from which the stiffness, the load at failure, and the relative elongation were determined. Additional mesh samples (n = 3) underwent a cyclic loading protocol to measure permanent elongation in response to subfailure loading. Results  With the exception of Popmesh, which displayed uniform stiffness, other meshes were characterized by a bilinear behavior. Newer meshes were 70–90% less stiff than Gynecare™ (p < 0.05) and more readily deformed in response to uniaxial and cyclical loading (p < 0.001). Conclusion  Relative to Gynecare™, the newer generation of prolapse meshes were significantly less stiff, with irreversible deformation at significantly lower loads.
Keywords:Mesh  Polypropylene  Prolapse
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