Synthesis of pyrazole-based 1,5-diaryl compounds as potent anti-inflammatory agents |
| |
| Authors: | Priyanka Shrivastava Praveen Singh Ashish Kumar Tewari |
| |
| Institution: | 1. Department of Chemistry, Faculty of Science, Banaras Hindu University, Varanasi, 221 005, India
|
| |
| Abstract: | Series of 1,5-diaryl pyrazole ester derivatives have been synthesized and found to contain potent inhibitory activity against cyclooxygenase-2 (COX-2) enzyme. The article describes synthesis of the target pyrazole analogs and biological assay using Carrageenan induced rat paw for investigation. |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
|
