| 响应面法优选桑黄总三萜的超声提取工艺 |
| |
| 引用本文： | 于小凤,秦庆玲,李峰,徐秀泉.响应面法优选桑黄总三萜的超声提取工艺[J].中国药房,2012(47):4455-4458. |
| |
| 作者姓名： | 于小凤 秦庆玲 李峰 徐秀泉 |
| |
| 作者单位： | 江苏大学药学院;江苏大学京江学院;江苏大学附属医院 |
| |
| 基金项目： | 江苏大学学生科技课题立项项目(09A177) |
| |
| 摘 要： | 目的：优化桑黄总三萜的超声提取工艺。方法：在单因素试验基础上,根据中心组合试验设计原理,以乙醇浓度、超声时间、超声温度为考察因素,以总三萜得率为评价指标,利用响应面法优选工艺。结果：最佳提取工艺为采用70%乙醇作提取溶剂,料液比为1∶20（g/mL）,于60℃超声提取21min。在此最佳条件下,总三萜得率为9.80mg·g-1。结论：试验结果与模型预测值相符,表明优选的提取工艺合理、可行。
|
| 关 键 词： | 桑黄 总三萜 超声提取 响应面设计 |
Optimization of Ultrasonic Extraction of Total Triterpenoids from Phellinus igniarius by Response Surface Methodology |
| |
| YU Xiao-feng, XU Xiu-quan.Optimization of Ultrasonic Extraction of Total Triterpenoids from Phellinus igniarius by Response Surface Methodology[J].China Pharmacy,2012(47):4455-4458. |
| |
| Authors: | YU Xiao-feng XU Xiu-quan |
| |
| Institution: | (School of Pharmacy, Jiangsu University, Jiangsu Zhenjiang 212013, China) QIN Qing-ling(School of Jingjiang, Jiangsu University, Jiangsu Zhenjiang 212013, China) LI Feng(The Affiliated Hospital of Jiangsu University, Jiangsu Zhenjiang 212001, China) |
| |
| Abstract: | OBJECTIVE： To optimize the ultrasonic extraction of total triterpenoids from Phellinus igniarius by response surface methodology. METHODS： Based on single factor test, the extraction technology was optimized by response surface methodology with concentration of ethanol, ultrasonic temperature and ultrasonic time as factors and the yield of total triterpenoids as index. RESULTS： The optimized technology was as follows： 70% ethanol as solvent, ratio of material to liquid 1 ∶ 20（g/mL）, extracting for 21 min at 60 ℃ The yield of total triterpenoids was 9.80 mg·g-1 under optimal condition. CONCLUSION： The result of trial is agreed with model predictions, which indicates the extraction technology is reasonable and feasible. |
| |
| Keywords: | Phellinus igniarius Total triterpenoids Ultrasonic extraction Response surface methodology |
| 本文献已被 CNKI 维普 等数据库收录！ |
|
