正常人群胸腰段椎体楔变指数的MRI测量

背景：虽然MRI在脊柱创伤中广泛应用，但国内尚未建立正常人群胸腰段椎体的MRI形态学参数。目的：利用 MRI 观测健康人群胸腰段椎体的楔变指数，为胸腰段压缩骨折和正常人楔形变的鉴别诊断提供MRI形态学依据。方法：征集2011年11月至2013年8月20-50岁健康志愿者120名，利用1.5T磁共振成像仪对志愿者行胸腰段扫描。在快速自旋回波T2WI正中矢状位上测量T11-L2椎体前缘高径、后缘高径，并计算楔形变指数。结果与结论：T11-L2椎体楔形变指数分别为0.91±0.05，0.91±0.05，0.88±0.08，0.91±0.08。T11-L2椎体存在楔形变的椎体个数分别为103个（23.52%），112个（25.57%），115个（26.26%），108个（24.66%）。各年龄组间楔形变指数值差异无显著性意义，但年龄较大者楔形变指数较小。男性志愿者楔形变指数值小于女性志愿者。重体力劳动者T11、L2楔变指数小于非重体力劳动者。楔形变指数与身高及体质量指数呈负相关。结果可见正常人群胸腰段椎体存在不同程度的楔形改变，并且楔变程度与多种因素有关。

Wedging index of thoracolumbar vertebrae in healthy persons measured by magnetic resonance imaging

BACKGROUND：MRI was extensively used in spinal trauma, but morphological parameters of MRI on thoracolumbar segments of normal persons were not established in China. OBJECTIVE： To measure wedging index of thoracolumbar vertebra in healthy population using MRI, and to proved MRI morphology data for differentialy diagnosing thoracolumbar vertebra fracture and wedging of normal persons. METHODS： 120 healthy volunteers aged 20-50 years old were recruited from November 2011 to August 2013. Al volunteers underwent 1.5T MRI scan for thoracolumbar vertebra. Heights of leading and trailing edges of T11-L2 vertebrae were measured using sagittal fast spin-echo T2WI and wedging index was calculated. RESULTS AND CONCLUSION：Wedging indexes of T11-L2 vertebrae were respectively 0.91±0.05, 0.91±0.05, 0.88±0.08 and 0.91±0.08. Numbers of wedging of T11-L2 vertebrae were respectively 103 （23.52%）, 112 （25.57%）, 115 （26.26%） and 108 （24.66%）. No significant difference in wedging indexes was detected among groups, but wedging index was smal in older volunteers. Wedging indexes were smaler in males than females. Wedging indexes of T11 and L2 were smaler in heavy manual workers than in non-heavy manual workers. Wedging indexes were associated with height and body mass index. Results indicated that wedging changes to different degrees existed in thoracolumbar vertebrae of normal persons, and the degree of wedging was correlated with many factors.