可膨胀桥拱式椎间融合器的生物学特性

背景：随着脊柱内窥镜等微创技术的发展,各种融合器尤其是膨胀式融合器成为一个研究热点。目的：介绍自行研制的用于治疗腰椎退行性疾病新的＂可膨胀桥拱式椎间融合器＂的设计理念和生物学特性。方法：在万方数据库、中国生物医学数据库、中文科技期刊数据库中检索2000年1月至2011年4月有关融合器应用于腰椎退行性疾病的研究文章,关键词为＂腰椎退行性疾病,融合器＂。分析目前融合器存在的不足,从而提出一种治疗腰椎退行性疾病的新型融合器的构想。结果与结论：经检索共查到相关文献50篇,排除筛选后纳入34篇进行评价。结合文献检索结果,提示了理想的膨胀式椎间融合器除体积小巧、便于植入等特性外,还应提供足够强度的椎体间支撑及稳定性,可有效防止植入后椎间隙高度丢失。参考以上条件,依据现有技术改良,研制出＂可膨胀桥拱式椎间融合器＂,十分便于微创植入,稳定性好,防下沉能力强,有很好的应用前景。

Biological properties of expandable bridge-arch interbody fusion cage

BACKGROUND： As spine endoscope and other microinvasive techniques develop, various fusion cages in particular expanded cage become the hot topic. OBJECTIVE： To introduce the design concept and biological characteristics of the novel expandable bridge-arch interbody fusion cage to treat lumbar degenerative disease. METHODS： A computer-based online search of Wanfang, CMB and VIP databases was performed for articles published between January 2000 and April 2011 related to the application of fusion cages in lumbar degenerative disease, with key words ＂lumbar degenerative disease, interbody fusion cage＂. Insufficiency in present cages was analyzed and a novel cage should be designed. RESULTS AND CONCLUSION： A total of 50 relevant literatures were collected, and 27 were included. Results showed that ideal expandable cage should have small size, convenience to placement, excellent biomechanical stability, and prevent postoperative loss of intervertebral height. Therefore, this novel expandable bridge-arch interbody fusion cage was developed. The novel cage has a very good perspective of application for many advantages, such as mini-invasive implantation, excellent stability and powerful ability to prevent sink.