hsCRP水平在无保护左主干冠状动脉病变介入治疗后再狭窄的评估价值

目的 探讨超敏C反应蛋白(hsCRP)水平与无保护左主干冠状动脉(ULMCA)病变行经皮冠状动脉介入治疗(PCI)术后再狭窄的关系.方法 76例ULMCA病变患者常规行冠状动脉造影(CAG)及支架置入,术前测定外周血hsCRP并依其水平分组,术后随访观察临床主要不良心血管事件(MACE)和CAG再狭窄发生率.结果 术前外周血hsCRP水平正常(＜3.0 mg/L)组22例,术后再狭窄发生率6.7%(1/15);hsCRP升高(3.0～3.9 mg/L)组33例,术后再狭窄发生率11.1%(2/18);hsCRP明显升高(≥4.0 mg/L)组21例,术后再狭窄发生率30.0%(6/21).组间比较,P＞0.05.结论 冠脉再狭窄发生率有随术前hsCRP升高而增加的趋势.

Relationship of preprocedural high sensitivity C-reactive protein and restenosis after coronary angioplasty of unprotected left main coronary artery stenosis

Objective To investigaye the relationship of preprocedural high sensitivity C-reactive protein (hsCRP) and restenosis after coronary angioplasty of unprotected left main coronary artery(ULMCA)stenosis.Methods Seventy-six patients with ULMCA stenosis were treated with stents and followed up.hsCRP of peripheral blood was measured before stenting.Results According to hsCRP levels,the patients were divided into throe groups of A(hsCRP＜3.0 mg/L,22cases),B(hsCRP 3.0-3.9 mg/L,33 cases)and C(hsCRP≥4.0 mg/L,21 cases).The rates of coronary restenosis were 6.7%(1/15)in group A,11.1%(2/18)in group B,and 30.0%(6/21)in group C(P＞0.05).Conculsion There is a tendency of increased incidence rate of restenosis after ULMCA stenting as increased levels of hsCRP before stenting.