| 整合素与肿瘤侵袭和转移的研究进展 |
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| 引用本文： | 季洪波,博晓真. 整合素与肿瘤侵袭和转移的研究进展[J]. 内蒙古医学院学报, 2005, 27(4): 346-349 |
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| 作者姓名： | 季洪波 博晓真 |
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| 作者单位： | 内蒙古医学院,免疫学教研室,内蒙古,呼和浩特,010059 |
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| 摘 要： | 整合素（integrin）属于细胞黏附分子家族，研究发现整合素可以调节细胞与细胞之间、细胞与细胞外基质（ECM）之间的黏附．然而不同整合素黏附作用也有明显不同．在肿瘸发生的不同阶段．整合素既可以抑制又可以促进肿瘤的侵袭和转移．本文就整合素的结构、分类、信号传导以及不同功能对肿瘤的侵袭和转移的影响做一综述。
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| 关 键 词： | 整合素 肿瘤 侵袭 转移 |
| 文章编号： | 1004-2113（2005）04-0346-04 |
| 收稿时间： | 2005-07-17 |
| 修稿时间： | 2005-09-21 |
THE STUDY ON THE RELATIONSHIP BETWEEN INTEGRINS AND TUMOR INVASION & METASTASIS |
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| JI Hong-bo,BO Xiao-zhen. THE STUDY ON THE RELATIONSHIP BETWEEN INTEGRINS AND TUMOR INVASION & METASTASIS[J]. Acta Academiae Medicinae Neimongol, 2005, 27(4): 346-349 |
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| Authors: | JI Hong-bo BO Xiao-zhen |
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| Affiliation: | Department of Immunology, Inner Mongolia Medical College, Hohhot 010059 China |
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| Abstract: | Integrins belong to cellular adhesion molecule family,which can regulate adhesion between cells and that between cell and extracellular matrix.But different integrin's adhesion is different.Integrins can not only promote but also restrain invasion and metastasis of tumor in different processes.The influence of integrins structure,classification,signal conduction, different functions on invasion and metastasis of tumor is reviewed in this article. |
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| Keywords: | integrin tumor invasion metastasis |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
