Allelic frequency of the MCP-1 promoter -2518 polymorphism in the Korean population and in Korean patients with rheumatoid arthritis, systemic lupus erythematosus and adult-onset Still's disease. |
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| Authors: | S-Y Hwang M-L Cho B Park J-Y Kim Y-H Kim D-J Min J-K Min H-Y Kim |
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| Affiliation: | Institute of Immunobiology, Catholic Institutes of Medical Science, The Catholic University of Korea, Seoul, Korea. dutuya@cmc.cuk.ac.kr |
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| Abstract: | The frequency of the monocyte chemoattractant protein-1 (MCP-1) -2518 G-type polymorphism in Koreans is significantly higher than the frequencies reported for Caucasians and Afro-Americans. The G- vs. A-allele profile in patients with systemic autoimmune diseases is similar to that in healthy Koreans, and does not appear to contribute to elevated MCP-1 production in patients. |
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