川参通直接注入前列腺治疗慢性非细菌性前列腺炎/慢性盆腔疼痛综合征

目的:观察川参通直接注入前列腺治疗慢性非细菌性前列腺炎/慢性盆腔疼痛综合征(CABP/CPPS)的疗效与安全性。方法:用川参通及利多卡因注射液5 m l,经会阴注射至前列腺,每日1次,共6次,治疗98例CABP/CPPS患者。采用美国国立卫生研究院(NIH)制定的前列腺炎症状评分(CPSI)标准判定疗效。结果:观察12周,治愈53例(54.08%),显效17例(17.35%),有效23例(23.47%),总显效率71.43%,总有效率94.90%。川参通治疗前后,CPSI疼痛评分、排尿症状评分、生活质量评分及总分均有显著改善(95%可信区间分别为:6.83~9.41,2.16~3.94,2.95~5.43,12.85~17.91)。结论:经会阴前列腺内注射川参通治疗CABP/CPPS有效、安全。

The Efficacy and Safety in the Treatment of Chronic Abacterial Prostatitis/Chronic Pelvic Pain Syndrome after Intraprostatic Injection of Chuanshentong

Objective: To assess the clinic efficacy and safety in the treatment of chronic abacterial prostatitis/chronic pelvic pain syndrome(CABP/CPPS) after intraprostatic injection of Chuanshentong. Methods: Five milliter of solution blending Chuanshentong and lidocaine was transperineally injected into one lobe of prostate,once a day for 6 days,for a total of 98 cases of patients who had been diagnosed as chronic abacterial prostatitis /chronic pelvic pain syndrome.The efficacy was evaluated by the NIH Chronic Prostatitis Symptom Index(CPSI) after a 12 week follow-up. Results: All cases had completed the follow-up.Fifty-three cases((54.08)%) were completely cured,accompanied by remarkable effective in 17 cases((17.35)%) and improved in 23 cases((23.47)%).The total remarkable efficacy was(71.43)% and improved(94.90)%.Scores of CPSI decreased significantly compared with pre-treatment(95% confidence interval(12.85)~(17.91)).Conclusion: It is suggested that transperineally intraprostatic injection of Chuanshentong may be a useful method for the treatment of CABP/CPPS.