垂体微腺瘤的诊断和单鼻孔经蝶显微手术治疗的探讨

目的探讨垂体微腺瘤（直径≤1.0cm）的早期诊断及单鼻孔经蝶入路显微手术切除的临床效果、手术适应症。方法回顾性分析36例行单鼻孔经蝶窦入路显微手术切除的垂体微腺瘤患者的影像学特征和临床特点。结果35例达到镜下全切除,1例大部分切除,并通过术后MRI增强扫描得到证实,且无严重手术并发症。平均随访22个月,患者临床症状较术前均有不同程度改善,手术效果良好。结论单鼻孔经蝶窦入路显微手术是治疗垂体微腺瘤治疗的可靠方法,具有切除彻底、创伤小、危险小、并发症少等优点。

Study on early diagnosis of pituitary microednoma and endonasel transsphenoidal microsurgery

Objective To explore the early diagnosis of pituitary microednoma（diameter ≤ 1.0 cm） and the clinic effect and operation indication of endonasal transsphenoidal microsurgery. Methods To analyze retrospectively the image feature and the clinical data of 36 patients with pituitary microadenomas treated by endonasal transsphenoidal microsurgery. Results Of the 36 eases, 35 received total tumor resection under the microscope and 1 subtotal tumor resection, which was confirmed by the MRI strengthening scanning after the operation and had no serious complications. Clinical symptoms in all cases were disappeared or improved significantly during the average 22 months of revisiting and the operations achieved satisfactory results. Conclusion The endonasal transsphenoidal microsurgery is a reliable method to treat pituitary microadenoma and has the advantages of thorough insection, micro-trauma, low risk and few complications.