中心性浆液性脉络膜视网膜病变的不同治疗疗效观察

目的 比较中心性浆液性脉络膜视网膜病变(中浆)的激光治疗与药物治疗的疗效.方法 选择门诊FFA造影确诊为中浆的64例69只眼,随机分为三组:激光治疗组21只眼,活血化瘀组23只眼,支持疗法组23只眼.激光治疗采用Omni多波长氪激光,活血化瘀采用复方血栓通胶囊,支持疗法采用复合VitB、肌苷、ATP.比较分析其随访3周、6周治疗效果以及平均治愈时间、最终随访视力,x2及t检验分析其统计学意义.结果 (1)激光治疗组随访3周与6周治愈率为66.7%和100%,平均治愈时间(±s)(2.81±0.65)w,最终随访视力1.08±0.11.(2)活血化瘀组随访3周与6周治愈率为26.0%和47.8%,平均治愈时间(7.23±4.51)w,最终随访视力0.98±0.15.(3)支持疗法组随访3周与6周治愈率为16.0%和32.0%,平均治愈时间(9.78±6.86)w,最终随访视力1.05±0.23.(4)激光治疗组与药物治疗组比较,3周与6周治愈率为P＜0.01,平均治愈时间P＜0.01,最终随访视力P＞0.05.(5)治愈后复发率,激光组4.4%,活血化瘀组17.3%,支持疗法组20%.结论 比较药物治疗,激光治疗中浆可提高治愈率,缩短治愈时间,降低复发率,但对最终视力恢复没有影响.

Abstract：

Objective To compare the efficacy of central serous chorioretinopathy by laser treatment and drug therapy. Methods Selected 69 outpatient with central serous chorioretinopathy (CSC) confirmed by imaging FFA were randomly divided into three groups: laser treatment group, 21 eyes, promoting blood circulation treatment group 23, and support therapy group 23. Omni multi-wavelength laser with krypton laser, promoting blood circulation by Fufang XueShuanTong capsule, supportive therapy with co-VitB, inosine, ATP.Comparative analysis of the follow-up 3 weeks, 6 weeks of treatment effect and the average healing time, the final follow-up vision, x2 and t test to analyze statistical significance. Results (1) laser treatment group was followed up for 3 weeks and 6 weeks the cure rate was 66.7% and 100%, the average healing time (x± s) 2.81± 0.65w, the final follow-up visual acuity 1.08 ± 0.11. (2) follow-up promoting blood circulation group 3weeks and 6 weeks the cure rate was 26.0% and 47.8%, the average healing time was 7.23 ± 4.51w, the final follow-up visual acuity 0.98 ± 0.15. (3) supportive care group were followed up for 3 weeks and 6 weeks the cure rate was 16.0% and 34.8%, The average healing time 9.78 ± 6.86 w, the final follow-up visual acuity 1.05± 0.23. (4) Laser treatment group compared with the drugs treatment group, 3 weeks and 6 weeks the cure rate was P ＜0.01, the average healing time was P ＜0.01, the final follow-up visual acuity P＞ 0.05. (5) the recurrence rate after cure, the laser group 4.4%, 17.3% blood circulation group to support the therapy group 20%. Conclusions Comparison of drug therapy, laser therapy can increase cure rate of central serous chorioretinupathy,shorten healing time, reduce the relapse rate, but do not affect the final visual acuity.

Clinical observation for central serous chorioretinopathy by laser treatment and drug therapy

Objective To compare the efficacy of central serous chorioretinopathy by laser treatment and drug therapy. Methods Selected 69 outpatient with central serous chorioretinopathy (CSC) confirmed by imaging FFA were randomly divided into three groups: laser treatment group, 21 eyes, promoting blood circulation treatment group 23, and support therapy group 23. Omni multi-wavelength laser with krypton laser, promoting blood circulation by Fufang XueShuanTong capsule, supportive therapy with co-VitB, inosine, ATP.Comparative analysis of the follow-up 3 weeks, 6 weeks of treatment effect and the average healing time, the final follow-up vision, x2 and t test to analyze statistical significance. Results (1) laser treatment group was followed up for 3 weeks and 6 weeks the cure rate was 66.7% and 100%, the average healing time (x± s) 2.81± 0.65w, the final follow-up visual acuity 1.08 ± 0.11. (2) follow-up promoting blood circulation group 3weeks and 6 weeks the cure rate was 26.0% and 47.8%, the average healing time was 7.23 ± 4.51w, the final follow-up visual acuity 0.98 ± 0.15. (3) supportive care group were followed up for 3 weeks and 6 weeks the cure rate was 16.0% and 34.8%, The average healing time 9.78 ± 6.86 w, the final follow-up visual acuity 1.05± 0.23. (4) Laser treatment group compared with the drugs treatment group, 3 weeks and 6 weeks the cure rate was P ＜0.01, the average healing time was P ＜0.01, the final follow-up visual acuity P＞ 0.05. (5) the recurrence rate after cure, the laser group 4.4%, 17.3% blood circulation group to support the therapy group 20%. Conclusions Comparison of drug therapy, laser therapy can increase cure rate of central serous chorioretinupathy,shorten healing time, reduce the relapse rate, but do not affect the final visual acuity.