| 白花银背藤抗炎作用研究 |
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| 引用本文： | 邱宏聪,李茂,李燕婧.白花银背藤抗炎作用研究[J].中国实验方剂学杂志,2011,17(9):207-208. |
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| 作者姓名： | 邱宏聪 李茂 李燕婧 |
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| 作者单位： | 广西中医药研究院,南宁,530022 |
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| 基金项目： | 广西科学研究与技术开发计划项目 |
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| 摘 要： | 目的:考察白花银背藤的抗炎作用。方法:将实验动物随机分为5组,每组10只,分别为模型对照组,阿司匹林组,白花银背藤高、中、低剂量组(按生药量计为19.0,13.6,8.2 g.kg-1),连续ig给药7 d,采用小鼠耳廊肿胀法、大鼠足跖肿胀法、大鼠棉球肉芽肿法考察抗炎作用。结果:白花银背藤能抑制巴豆油致小鼠耳肿胀(P<0.05～P<0.01),能抑制角叉菜胶致大鼠足跖肿胀(P<0.05),并能减轻大鼠棉球肉芽肿质量(P<0.05)。结论:白花银背藤具有一定的抗炎作用。
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| 关 键 词： | 白花银背藤 抗炎作用 大鼠 |
| 收稿时间： | 2010/11/30 0:00:00 |
Study on Anti-inflammatory Effect of Argyreia seguinii |
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| QIU Hong-cong,LI Mao and LI Yan-jing.Study on Anti-inflammatory Effect of Argyreia seguinii[J].China Journal of Experimental Traditional Medical Formulae,2011,17(9):207-208. |
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| Authors: | QIU Hong-cong LI Mao and LI Yan-jing |
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| Institution: | Guangxi Institute of Chinese Medicine and Pharmaceutical Science. Nanning 530022, China;Guangxi Institute of Chinese Medicine and Pharmaceutical Science. Nanning 530022, China;Guangxi Institute of Chinese Medicine and Pharmaceutical Science. Nanning 530022, China |
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| Abstract: | Objective: To study the anti-inflammation effect of Argyreia seguinii . Method: The animals were given orally with A. seguinii daily(at doses of 19.0,13.6,8.2 g ·kg-1 accordingly) for 7 days. Model of ear swelling in mice,model of paw edema in rats and model of cotton granuloma in rats were adopted to observe the anti-inflammatory effects. Result: A. seguinii could inhibit the ear swelling induced by the croton oil ( P <0.05 or P <0.01),inhibit the swelling of the paw in rats with the carrageenan ( P <0.05),and reduce the weight of cotton granuloma in rats ( P <0.05). Conclusion: The results indicates that A. seguinii has anti-inflammatory effect. |
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| Keywords: | Argyreia seguinii anti-inflammation effect rat |
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