外路小梁切开联合小梁切除术治疗原发性先天性青光眼疗效观察

目的 评价外路小梁切开联合小梁切除术治疗原发性先天性青光眼的临床疗效.方法 随访首次手术行外路小梁切开联合小梁切除术的原发性先天性青光眼患者66例(96只眼),观察术后眼压、角膜横径、杯/盘比值、滤过泡情况及手术并发症,并分析其临床疗效.结果 术后平均随访(11.76±8.5 1)个月,术后1个月、6个月、12个月手术成功率分别为95.83%、92.06%、87.23%.术后平均眼压较术前统计学降低(P＜0.01);杯/盘比值较术前明显减小(P＜0.01);角膜横径手术前后差异无显著意义(P=0.495);手术失败者角膜横径较术前增大(P＜0.05).手术并发症主要有不同程度的前房出血和术后浅前房等.结论 外路小梁切开联合小梁切除术是治疗原发性先天性青光眼安全有效的手术方式之一.

Abstract：

Objective To observe the therapeutic effect of external trabeculotomy combined with trabeculectomy for primary congenitalglaucoma.Methods Sixty-six cases (96 eyes) of primary congenital glaucoma patients treated with exter(n)al trabeculotomy combined with trabeculectomy were observed,the intraocular pressure,cornea diameter,C/D ratio,filter bleb and complication were observed pre- and post-operation,the therapeutic effect were analyzed.Results The mean follow up period wasl 1.76± 8.51months,the successful rate in 1 month,6 months and 12 months after operation was 95.83%,92.06%,87.23% respeectively.The intraocular pressure (IOP) was decreased markedly after operation (P ＜0.01).C/D ratio was decreased markedly (P ＜0.01).There was no statistical difference in cornea diameter between pre- and post-operation (P =0.495).The cornea diameter enlarged in those failed in operations.The complications were various degrees of hypema and shallow anterior chamber.Conclusions External trabeculotomy combined with trabeculectomy is a safe and effective way to treat primary congenital glaucoma.

Follow-up observation of therapeutic effect on external trabeculotomy combined with trabeculectomy for primary congenital glaucoma.

Objective To observe the therapeutic effect of external trabeculotomy combined with trabeculectomy for primary congenitalglaucoma.Methods Sixty-six cases (96 eyes) of primary congenital glaucoma patients treated with exter(n)al trabeculotomy combined with trabeculectomy were observed,the intraocular pressure,cornea diameter,C/D ratio,filter bleb and complication were observed pre- and post-operation,the therapeutic effect were analyzed.Results The mean follow up period wasl 1.76± 8.51months,the successful rate in 1 month,6 months and 12 months after operation was 95.83%,92.06%,87.23% respeectively.The intraocular pressure (IOP) was decreased markedly after operation (P ＜0.01).C/D ratio was decreased markedly (P ＜0.01).There was no statistical difference in cornea diameter between pre- and post-operation (P =0.495).The cornea diameter enlarged in those failed in operations.The complications were various degrees of hypema and shallow anterior chamber.Conclusions External trabeculotomy combined with trabeculectomy is a safe and effective way to treat primary congenital glaucoma.