Residential instability during adolescence and health and wellbeing in adulthood: A longitudinal outcome-wide study |
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| Affiliation: | 1. Department of Social & Behavioral Sciences, Harvard T.H. Chan School of Public Health, Boston, MA, USA;2. Center on the Developing Child, Harvard University, Cambridge, MA, USA;3. Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA;4. Human Flourishing Program, Harvard Institute for Quantitative Social Science, Cambridge, MA, USA;5. Department of Epidemiology and Prevention, Center for Clinical Sciences, National Center for Global Health and Medicine, Shinjukku, Tokyo, Japan;6. Department of Biostatistics, Harvard T.H.Chan School of Public Health, Boston, MA, USA;1. Department of International Health and Sustainable Development, Tulane University School of Public Health and Tropical Medicine, 1440 Canal St. Suite 2200, New Orleans, Louisiana, USA;2. University of Kinshasa School of Public Health, Faculty of Medicine, Kinshasa, Congo;1. MIVEGEC, Univ. Montpellier, CNRS, IRD, Montpellier, France;2. Odum School of Ecology, University of Georgia, Athens, GA, USA;3. Center for Ecology of Infectious Diseases, University of Georgia, Athens, GA, USA;4. Observatoire de Genève, Université de Genève, Sauverny, Switzerland;5. School of Arts and Sciences, Azim Premji University, Bengaluru, Karnataka, India;6. Department of Entomology, College of Agriculture and Life Sciences, Cornell University, Ithaca, NY, USA;7. Cornell Institute of Host-Microbe Interactions and Disease, Cornell University, Ithaca, NY, USA;8. Northeast Regional Center for Excellence in Vector-borne Diseases, Cornell University, Ithaca, NY, USA;9. Department of Geography, University of Georgia, Athens, GA, USA;10. Biological and Life Sciences Division, School of Arts and Sciences, Ahmedabad University, Ahmedabad, Gujarat, India;1. Columbia University, School of Social Work, New York, NY, USA;2. Rutgers, The State University of New Jersey, School of Social Work, New Brunswick, NJ, USA;3. Rutgers, The State University of New Jersey, Robert Wood Johnson Medical School, New Brunswick, NJ, USA;1. Social & Behavioural Research Unit, Department of Preventive and Social Medicine, University of Otago, PO Box 56, Dunedin, 9054, New Zealand;2. Biostatistics Centre, Division of Health Sciences, University of Otago, PO Box 56, Dunedin, 9054, New Zealand;3. Geospatial Research Institute, University of Canterbury, Private Bag 4800, Christchurch, 8140, New Zealand;4. Faculty of Environment, Society and Design, Lincoln University, PO Box 85084, Ellesmere Junction Road, Lincoln, 7647, Canterbury, New Zealand;5. Ngāi Tahu Māori Health Research Unit, Division of Health Sciences, University of Otago, PO Box 56, Dunedin, 9054, New Zealand |
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| Abstract: | Although prior research suggests that residential instability during adolescence can have long-term impacts on health and wellbeing, few studies have identified a robust comparison group and considered a broad set of outcomes. To address these knowledge gaps, we examined the associations between residential instability during adolescence and a wide range of adult health and wellbeing outcomes using an outcome-wide design in the National Longitudinal Study of Adolescent to Adult Health. We defined residential instability as two or more moves between Waves I and II (ages 13–18 years). We assessed outcomes at ages 33–43 years (Wave V) in nine domains: biomarkers, physical health, health behaviors, psychological distress, psychological wellbeing, social behaviors, social wellbeing, trauma/victimization, and socioeconomic attainment. Results of doubly-robust targeted maximum likelihood estimation, adjusting for pre-exposure values of the outcome variables and cofounders (Wave I), showed little evidence of an association for certain outcomes, all of which disappeared after accounting for multiple comparisons. Our results suggest that residential instability in adolescence does not lead to worse health and wellbeing in adulthood, but rather, outcome differences between groups are due to pre-existing differences prior to residential instability in adolescence. |
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| Keywords: | Adolescence Residential instability Life-course epidemiology Outcome-wide epidemiology |
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