左氧氟沙星序贯疗法治疗老年肺炎的效果观察

目的观察左氧氟沙星序贯疗法治疗老年肺炎患者的临床效果。方法选择我院2016年5月至2019年5月收治的老年肺炎患者60例,随机分为两组各30例。对照组采用左氧氟沙星静脉滴注,观察组采用左氧氟沙星静脉滴注转左氧氟沙星口服治疗。对比两组患者治疗前后的SAA、 CRP水平及不良反应发生率、临床症状消失时间、临床治疗效果。结果与对照组比较,观察组治疗后的SAA、 CRP水平较低,不良反应发生率较低,临床症状消失时间较短,治疗总有效率较高,差异均有统计学意义(P <0.05)。结论左氧氟沙星序贯疗法治疗老年肺炎的临床效果较好,不良反应较少,值得临床推广应用。

Observation on Effect of Levofloxacin Sequential Therapy in the Treatment of Senile Pneumonia

Objective To observe the clinical effect of levofloxacin sequential therapy in the treatment of elderly patients with pneumonia. Methods 60 elderly patients with pneumonia admitted to our hospital from May 2016 to May 2019 were selected and randomly divided into two groups, with 30 cases in each group. The control group was given intravenous infusion of levofloxacin, and the observation group was given intravenous infusion of levofloxacin then transferred to oral administration of levofloxacin. The SAA and CRP levels before and after treatment, the incidence of adverse reactions, disappearance time of clinical symptoms and clinical treatment effect were compared between the two groups. Results Compared with the control group, the SAA and CRP levels after treatment of the observation group were lower, the incidence of adverse reactions was lower, the disappearance time of clinical symptoms was shorter, and the total effective rate of treatment was higher, with statistical differences(P <0.05). Conclusions Levofloxacin sequential therapy has better clinical effect and fewer adverse reactions in the treatment of senile pneumonia, which is worthy of clinical promotion and application.