Pulmonary abscess caused by Cladosporium cladosporioides after receiving outpatient chemotherapy |
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| Affiliation: | 1. Department of Clinical Infectious Diseases, Toyama University Graduate School of Medicine and Pharmaceutical Sciences, Toyama, Japan;2. Department of Clinical Laboratory and Molecular Pathology, Toyama University Graduate School of Medicine and Pharmaceutical Sciences, Toyama, Japan;3. First Department of Internal Medicine, Toyama University Graduate School of Medicine and Pharmaceutical Sciences, Toyama, Japan;4. Department of Obstetrics and Gynecology, Toyama University Graduate School of Medicine and Pharmaceutical Sciences, Toyama, Japan;5. Department of Fungal Infection, National Institute of Infectious Diseases, Tokyo, Japan;1. Department of Medical Microbiology, Post graduate institute of medical education and research, Chandigarh, India;2. Department of Neurosurgery, Post graduate institute of medical education and research, Chandigarh, India;1. Key Laboratory of Animal Disease and Human Health of Sichuan Province, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, 611130, China;2. China Conservation and Research Center for the Giant Panda, Chengdu, Sichuan, 611800, China;3. College of Life Sciences, Sichuan Agricultural University, Chengdu, 611130, China;1. Disease Control and Prevention Center, National Center for Global Health and Medicine, Tokyo, Japan;2. Department of Infection Control, Graduate School of Medicine Faculty of Medicine, Osaka University, Osaka, Japan;3. Department of Infectious Diseases, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, Tokyo, Japan;4. Department of Infectious Diseases, Japanese Red Cross Narita Hospital, Chiba, Japan;5. Division of Infectious Diseases, Tokyo Bay Urayasu Ichikawa Medical Center, Chiba, Japan;6. Center for Clinical Science, National Center for Global Health and Medicine, Tokyo, Japan;7. Department of Refractory Viral Infections, National Center for Global Health and Medicine Research Institute, Tokyo, Japan;8. Joint Center for Researchers, Associates and Clinicians Data Center, Department of Data Science, Center for Clinical Sciences, National Center for Global Health and Medicine, Tokyo, Japan;9. Clinical Laboratory Department, National Center for Global Health and Medicine, Tokyo, Japan;10. Japanese Red Cross Central Blood Institute, Tokyo, Japan;11. Department of Infectious Diseases, Tokyo Metropolitan Bokutoh Hospital, Tokyo, Japan;12. Department of Respiratory Medicine, Tokyo Medical and Dental University, Tokyo, Japan;13. Department of Respiratory Medicine, JCHO Tokyo Shinjuku Medical Center, Tokyo, Japan;14. Department of Hematology, National Center for Global Health and Medicine, Tokyo, Japan;15. Department of Intractable Diseases, National Center for Global Health and Medicine, Tokyo, Japan;p. Department of Safety Research on Blood and Biological Products, National Institute of Infectious Diseases, Tokyo, Japan;q. Department of Microbiology, Faculty of Medicine, Kansai Medical University, Osaka, Japan;r. Japanese Red Cross Kanto-Koshin-etsu Block Blood Center, Tokyo, Japan;s. Center for Clinical Research, National Center for Child Health and Development, Tokyo, Japan;1. Department of Neurology, Laboratory for Neurotherapeutics, Seoul National University Hospital, College of Medicine, Seoul National University, Seoul, 03080, South Korea;2. Department of Genomic Medicine, Seoul National University Hospital, Seoul, 03080, South Korea;3. Department of Neurology, Dong-A University Hospital, Busan, 49315, South Korea |
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| Abstract: | Cladosporium cladosporioides is one of the most ubiquitous dematiaceous fungi that seldomly occur human infection. Here, we demonstrate a rare case of pulmonary phaeohyphomycosis with a distinctive pulmonary lesion during the nadir period of outpatient chemotherapy against endometrial cancer. In addition to severe neutropenia, excessive exposure to C. cladosporioides at patient's residence was considered as dominant causative factor. More caution is considered necessary for pulmonary phaeohyphomycosis in patients who receive outpatient chemotherapy and are homebound during neutropenic status. |
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| Keywords: | Phaeohyphomycosis Pulmonary abscess Neutropenia Chemotherapy BALF" },{" #name" :" keyword" ," $" :{" id" :" pc_ZpGrh9rJCw" }," $$" :[{" #name" :" text" ," _" :" bronchoalveolar lavage fluid CFPM" },{" #name" :" keyword" ," $" :{" id" :" pc_GfdMgikRVX" }," $$" :[{" #name" :" text" ," _" :" cefepime COP" },{" #name" :" keyword" ," $" :{" id" :" pc_p40ii7hjCA" }," $$" :[{" #name" :" text" ," _" :" cryptogenic organizing pneumonia CT" },{" #name" :" keyword" ," $" :{" id" :" pc_hLleCkFd07" }," $$" :[{" #name" :" text" ," _" :" computed tomography GGO" },{" #name" :" keyword" ," $" :{" id" :" pc_RmdbCj0eCX" }," $$" :[{" #name" :" text" ," _" :" ground glass opacity ITCZ" },{" #name" :" keyword" ," $" :{" id" :" pc_YhCnMwLclk" }," $$" :[{" #name" :" text" ," _" :" itraconazole RHS" },{" #name" :" keyword" ," $" :{" id" :" pc_YC5uiqpGZV" }," $$" :[{" #name" :" text" ," _" :" reversed halo sign VCM" },{" #name" :" keyword" ," $" :{" id" :" pc_i5QsjMX9b4" }," $$" :[{" #name" :" text" ," _" :" vancomycin VRCZ" },{" #name" :" keyword" ," $" :{" id" :" pc_YZQojsvynO" }," $$" :[{" #name" :" text" ," _" :" voriconazole |
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