米非司酮在妇科疾病治疗中的研究进展

米非司酮是一种作用于受体水平的孕激素拮抗剂,其在临床上主要应用于生殖医学上的调节月经、紧急避孕和终止早期妊娠等方面.近年来研究发现米非司酮具有抑制细胞增殖和促进细胞凋亡的能力,可以用于抑制妇科恶性肿瘤和因细胞过度增长引起的子宫内膜异位和子宫肌瘤等妇科疾病的治疗.该文就米非司酮在妇科疾病治疗中的作用作一综述.

Research progress of mifepristone in the treatment of gynecological diseases

Mifepristone is a progestational hormone antagonist affecting the level of receptor,which is mainly applied inmenstruation reg-ulation,emergency contraception and the termination of early pregnancy and other aspects in clinical practice of reproductive medicine. Recent studies have found that mifepristone has the ability to inhibit cell proliferation and promote apoptosis,so it can be used to inhibit gynecological malignancies,and treat endometriosis and uterine fibroids caused by the excessive cell growth.This article is a review of mifepristone's effect in the treatment of gynecological diseases.