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他汀类66例药品不良反应报告分析
引用本文:杨波,王来成. 他汀类66例药品不良反应报告分析[J]. 安徽医药, 2017, 21(1): 186-188. DOI: 10.3969/j.issn.1009-6469.2017.01.052
作者姓名:杨波  王来成
作者单位:徐州市食品药品监督管理局,江苏徐州,221018;徐州医科大学附属医院药学部,江苏徐州,221006
摘    要:目的 为促进临床更合理地使用他汀类药品,为其临床安全用药提供参考依据.方法 汇总徐州市2015年1月—2016年6月66例他汀类药品的不良反应报告进行回顾性分析和总结.结果 60岁以上病人服用他汀类药品不良反应发生率最高,其中以胃肠道反应最为常见,使用辛伐他汀发生不良反应发生率最高.结论 他汀类药品应从小剂量开始服用,加强监测,确保病人用药安全、有效.

关 键 词:他汀类药品  不良反应  合理用药
收稿时间:2016-08-04
修稿时间:2016-11-21

Analysis of 66 cases of adverse drug reactions induced by statins
YANG Bo and WANG Laicheng. Analysis of 66 cases of adverse drug reactions induced by statins[J]. Anhui Medical and Pharmaceutical Journal, 2017, 21(1): 186-188. DOI: 10.3969/j.issn.1009-6469.2017.01.052
Authors:YANG Bo and WANG Laicheng
Affiliation:Xuzhou Food and Drug Administration,Xuzhou,Jiangsu 221018,China and Department of Pharmacy, The Affiliated Hospital of Xuzhou Medical University,Xuzhou,Jiangsu 221006,China
Abstract:Objective To contribute to using statins rationally and to provide references for the clinical safe medication.Methods Retrospective study on adverse drug reactions of 66 cases in Xuzhou from January 2015 to June 2016 were analyzed and summarized. Results Highest incidence of adverse reactions occurred among patients above 60 years old.Gastrointestinal reaction induced by st-atinswas the most common adverse reactions.Simvastatin induced the highest incidence of adverse reactions.Conclusion Statins should be taken from small doses and monitoring should be enhanced,which can ensure the safety and efficiency of the drug.
Keywords:Statins  Adverse reactions  Rational drug use
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