| 104例肿瘤病人药品不良反应发生特点分析 |
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| 引用本文： | 张霓,赵秀莉.104例肿瘤病人药品不良反应发生特点分析[J].安徽医药,2017,21(2):368-370. |
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| 作者姓名： | 张霓 赵秀莉 |
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| 作者单位： | 郑州大学附属肿瘤医院药学部,河南 郑州,450008;郑州大学附属肿瘤医院药学部,河南 郑州,450008 |
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| 摘 要： | 目的 探讨肿瘤病人住院期间药品不良反应(ADR)的发生规律和特点,为临床安全、合理用药提供依据.方法 对104例肿瘤病人发生ADR的病例按病人年龄、性别、给药途径、药品类型、ADR 涉及器官和(或)系统及临床表现等进行分类统计与分析.结果 104例药品不良反应报告中,静脉给药导致药品不良反应为96.15%;由抗肿瘤药物引起的药品不良反应最多,占48.08%;不良反应临床表现以皮肤及附件损害最为常见,占24.41%.结论 医院应加强与重视肿瘤病人药品不良反应的监测工作,保证肿瘤病人用药的安全性.
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| 关 键 词： | 肿瘤病人 药品不良反应 特点 分析 |
| 收稿时间： | 2016/9/27 0:00:00 |
| 修稿时间： | 2016/10/19 0:00:00 |
Adverse drug reactions in tumor patients:analysis of 104 cases |
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| ZHANG Ni and ZHAO Xiuli.Adverse drug reactions in tumor patients:analysis of 104 cases[J].Anhui Medical and Pharmaceutical Journal,2017,21(2):368-370. |
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| Authors: | ZHANG Ni and ZHAO Xiuli |
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| Institution: | Department of Pharmacy,Affiliated Cancer Hospital of Zhengzhou University,Zhengzhou,Henan 450008,China and Department of Pharmacy,Affiliated Cancer Hospital of Zhengzhou University,Zhengzhou,Henan 450008,China |
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| Abstract: | Objective To discuss the characteristics and regularities of the adverse drug reaction (ADR) occurred in tumor patients.Methods Statistics analysis were conducted with 104 cases collected from the ADR,based on patient age,sex,route of administration,ADR extent,drug type,ADR involving organ or system and classification of clinical manifestations.Results In 104 ADR cases,96.15% cases were intravenous injection.48.08% cases were relate to antineoplastic.ADR were mainly manifested as skin and local lesion(24.41%).Conclusions It is important to strengthen the consciousness on rational drug use based on the characteristics of tumor patients to ensure medication safety. |
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| Keywords: | Tumor patients Adverse drug reaction (ADR) Characteristic Analysis |
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