| 幼年特发性关节炎合并巨噬细胞活化综合征的药物治疗进展 |
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| 引用本文： | 曹璐,许静,张永,景霞,湛雯,徐进. 幼年特发性关节炎合并巨噬细胞活化综合征的药物治疗进展[J]. 安徽医药, 2017, 21(4): 600-604. DOI: 10.3969/j.issn.1009-6469.2017.04.004 |
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| 作者姓名： | 曹璐 许静 张永 景霞 湛雯 徐进 |
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| 作者单位： | 南京医科大学附属儿童医院,江苏 南京,210008;南京医科大学附属儿童医院,江苏 南京,210008;南京医科大学附属儿童医院,江苏 南京,210008;南京医科大学附属儿童医院,江苏 南京,210008;南京医科大学附属儿童医院,江苏 南京,210008;南京医科大学附属儿童医院,江苏 南京,210008 |
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| 摘 要： | 巨噬细胞活化综合征(MAS)是幼年特发性关节炎(JIA)并发症的一种,严重者可致命.目前,临床上尚无治疗该并发症的应用指南.该文综述了幼年特发性关节炎合并MAS的药物治疗进展,包括传统治疗JIA的药物以及新型生物制剂.旨在临床为该病的治疗提供用药指导.
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| 关 键 词： | 幼年特发性关节炎 巨噬细胞活化综合征 传统药物 新型生物制剂 |
| 收稿时间： | 2016-07-25 |
| 修稿时间： | 2016-11-25 |
Advances in drug therapy for juvenile idiopathic arthritis combined with macrophage activation syndrome |
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| CAO Lu,XU Jing,ZHANG Yong,JING Xi,ZHAN Wen and XU Jin. Advances in drug therapy for juvenile idiopathic arthritis combined with macrophage activation syndrome[J]. Anhui Medical and Pharmaceutical Journal, 2017, 21(4): 600-604. DOI: 10.3969/j.issn.1009-6469.2017.04.004 |
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| Authors: | CAO Lu XU Jing ZHANG Yong JING Xi ZHAN Wen XU Jin |
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| Abstract: | Macrophage activation syndrome (MAS) is a serious fatal complication of rheumatic diseases,which is seen most frequently in systemic juvenile idiopathic arthritis (JIA).Up to now,there are no clinical application guidelines for the treament of such complication.Here,this paper reviewed the drug of JIA combined with MAS treatment,including the traditional medicines used in JIA and the new biological agents,which aimed to provide guidance of rational drug use for clinics. |
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| Keywords: | Juvenile idiopathic arthritis Macrophage activation syndrome Traditional medicines New biological agents |
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