合肥市40岁以上社区人群代谢综合征的患病现状及危险因素分析

目的 了解合肥市社区人群代谢综合征(MS)的患病现状及其相关危险因素.方法 针对中国糖尿病与肿瘤发生风险的前瞻性随访研究的基线调查资料,排除部分数据缺失、误差,选取有年龄、性别、既往史、身高、体重、腰臀围、血糖、血脂、血压等具有完整资料的40岁以上人群共9977例进行分析.代谢综合征诊断标准采用2007年《中国成人血脂异常防治指南》修订定义.将调查对象分为正常组和MS组,采用t检验和χ2检验比较两组之间年龄、性别、血脂、体质指数(BMI)等指标的差异,采用Logistic回归分析MS发病的相关危险因素.结果 合肥市40岁以上社区居民MS的粗患病率为27.6℅,标化患病率为26.6℅.MS患病率随着年龄增加逐渐增高,MS组患者血压、腰臀比、BMI、糖化血红蛋白等指标均较正常人群增高,差异均有统计学意义(P<0.05).多因素回归分析结果显示年龄、BMI、三酰甘油是MS的独立危险因素,而高密度脂蛋白胆固醇是代谢综合征的保护性因素.结论 MS发病率较高,与多种因素有关,应针对相关危险因素积极采取干预措施,预防疾病发生.

Analysis of prevalence and risk factors of metabolic syndrome in Hefei community population aged over 40

Objective To determine the prevalence and risk factors for metabolic syndrome ( MS) in the communi-ty population in Hefei. Methods Based on the data collected in the baseline survey and REACTION research, af-ter elimination of miss and errors, a total of 9977 patients were selected, who were aged≥40 years with complete data including age, gender, medical history, height, weight, waist-hip ratio, blood sugar, blood lipid and blood pressure. Participants were divided into two groups ( normal and MS) , and MS patients were screened by Chinese guidelines on dyslipidemia in adults 2007. Chi-square test and t test were engaged to test for age, sex, blood lipids and body mass index ( BMI) differences between the two groups. Logistic regression was served to analyze the risk factors for MS. Results Crude prevalence ratio and standardized prevalence ratio of MS patients in Hefei commu-nity populations ( age>40 years) were 27. 6℅ and 26. 6℅, respectively. The prevalence ratio for MS patients in-creased with aging. The values of blood pressure, waist-hip ratio, BMI and HbA1C were significantly increased in MS group, as compared with the corresponding values in the control group (P<0. 05). Age, BMI and triglyceride were independent risk factors for MS. High-density lipoprotein was a protection factor for MS. Conclusion High prevalence ratio for MS is associated with multiple factors. Strategies aimed at MS-related risk factors may be bene-ficial to prevent against MS.