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Adjuvant action of fragments of the IgG molecule present in the serum of partially hepatectomized rabbits
Authors:D N Evnin  I A Tarkhanova  A Ya Kul'berg
Abstract:Fragments of the IgG molecule, related to Fab, present in the blood serum of partially hepatectomized rabbits, have the property of intensifying the immune response of rabbits through xenogeneic erythrocytes. After simultaneous injection of sheep's erythrocytes and the Fab-like fragment into rabbits there was an increase in the number of antibody-producing cells in the spleen and in the titers of 19S and 7S hemagglutinins.Kursk Medical Institute. N. F. Gamaleya Institute of Epidemiology and Microbiology, Academy of Medical Sciences of the USSR, Moscow. (Presented by Academician of the Academy of Medical Sciences of the USSR G. V. Vygodchikov.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 81, No. 2, pp. 206–208, February, 1976.
Keywords:partial hepatectomy  F(ab')2 fragment of autologous IgG  immune response
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