Analog Electrical Model of the Coronary Circulation in Case of Multiple Revascularizations |
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Authors: | Mahmoud Maasrani Jean-Philippe Verhoye Herve Corbineau Agnes Drochon |
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Institution: | (1) Department of Biomedical Engineering, IUL University, Beirut, Lebanon;(2) Department of Thoracic and Cardiovascular Surgery, Rennes Hospital Center, Inserm U642, Rennes , France;(3) UMR CNRS 6600 “Biomechanics and Bioengineering”, University of Technology of Compiègne, 60200 Compiegne, France |
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Abstract: | In this work, we propose an analog electrical model of the coronary circulation for patients with obstructive disease undergoing
revascularization. In this clinical situation, the collateral circulation to the occluded artery is difficult to ascertain
via preoperative measurements and well-developed collaterals might induce long-term restenosis of the revascularized artery
due to flow competition mechanisms. The proposed model allows an original biomechanical analysis of per-operative hemodynamic
data in order to assess quantitative evaluation of pressures and flows inside the native stenosed arteries, the collateral
network and the bypass grafts. Average cardiac cycle values are analysed. In the case of 3-vessel disease and chronic occlusion
of the right coronary artery, the quantitative results confirm the protective effects of the collateral flows in the pathological
situation, but also show that the revascularization of the occluded right artery is fully justified since the collateral flows
remain low, even when the left territory is revascularized. The model thus provides a computational tool to evaluate therapeutic
strategies for each patient. |
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Keywords: | Coronary artery bypass graft Analog electrical model Collateral blood flow Matlab simulation |
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