白竭散治疗肛周脓肿合并糖尿病术后创面22例

目的观察白竭散治疗肛周脓肿合并糖尿病术后创面的疗效。方法将44例肛周脓肿合并糖尿病的患者随机分为治疗组和对照组,每组各22例。两组病例常规给予降糖和抗感染治疗,治疗组术后创面用白竭散换药,对照组予凡士林纱条换药。分别观察两组病例术后7、14d创面疼痛程度、渗液情况、创面愈合率、成纤维细胞数量。结果两组病例术后7d创面疼痛程度、渗液情况比较,差异有统计学意义(P0.05),创面愈合率、成纤维细胞数量比较,差异无统计学意义(P0.05);术后14d创面疼痛程度、渗液情况比较,差异无统计学意义(P0.05),创面愈合率、成纤维细胞数量比较,差异具有统计学意义(P0.05)。结论白竭散治疗肛周脓肿合并糖尿病的术后创面,早期能减轻疼痛、减少渗液,后期有促进创面愈合的作用。

Therapeutic Effect of Baijie Powder on Postoperative Wound in Perianal Abscess Patients with Diabetes: A Report of 22 Cases

Objective To observe the therapeutic effect of Baijie Powder on the postoperative wound in perianal abscess patients with diabetes. Methods Forty-four perianal abscess patients with diabetes were randomly divided into treatment group (n=22) and control group (n=22). Both groups received antidiabetic and anti-infective therapy. During dressing change, Baijie Powder was applied in the treatment group, and vaseline gauze was used in the control group. The treatment outcomes of the two groups were evaluated based on the degrees of wound pain, effusion, rates of wound healing, and numbers of fibroblasts at 7th and 14th day after operation. Results At 7 d after operation, the treatment group had a significantly lower degree of wound pain and significantly less effusion than the control group (P<0.05), but there were no significant differences in rate of wound healing and number of fibroblasts between the two groups (P>0.05). At 14 d after operation, there were no significant differences in degree of wound pain and effusion between the two groups (P>0.05), but the treatment group had a significantly higher rate of wound healing and a significantly larger number of fibroblasts than the control group (P<0.05). Conclusion Baijie Powder can be used for treating the postoperative wound in perianal abscess patients with diabetes. It can alleviate wound pain and reduce effusion early after operation and promote wound healing later.