Seroprevalencia de enfermedad de Lyme en el suroccidente de Asturias |
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| Institution: | 1. Servicio de Microbiología, Hospital Carmen y Severo Ochoa, Cangas del Narcea, España;2. Servicio de Microbiología, Hospital Universitario Central de Asturias, Oviedo, España;3. Centro Comunitario de Sangre y Tejidos de Asturias, Oviedo, España;1. National Reference Centre for Borrelia, Consultant Laboratory for Ehrlichia (until 2013), Bavarian Health and Food Safety Authority, Veterinärstr. 2, 85764 Oberschleißheim, Germany;2. Applied Epidemiology, Robert Koch Institute, DGZ-Ring 1, 13086 Berlin, Germany;1. Central Research Institute for Epidemiology (CRIE), Federal Service on Consumer Rights Protection and Human Well-Being Surveillance, Moscow, Russia;2. Research Institute of Occupational Health, Moscow, Russia;3. I.M. Sechenov First Moscow Medical University, Moscow, Russia;4. Altai State Medical University, Barnaul, Russia;1. Department of Respiratory Medicine, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, China;2. Department of Microbiology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, China;1. Institute for Parasitology, Centre for Infection Medicine, University of Veterinary Medicine Hannover, Buenteweg 17, 30559 Hannover, Germany;2. Immunology Unit und Research Center for Emerging Infections and Zoonoses, University of Veterinary Medicine Hannover, Buenteweg 17, 30559 Hannover, Germany;3. National Reference Center for Borrelia, Bayerisches Landesamt für Gesundheit und Lebensmittelsicherheit (LGL), Veterinaerstraße 2, 85764 Oberschleißheim, Germany |
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| Abstract: | IntroductionTo correctly interpret the serological markers of Lyme disease, it is very important to determine the region's infection rate. The aim of this study was to ascertain the prevalence of specific antibodies against Borrelia burgdorferi in a rural district in northern Spain.MethodsThe presence of IgG antibodies against B. burgdorferi was determined by qualitative enzyme immunoassay in the serum of 1,432 people divided into 3 groups: 316 blood donors, 432 individuals who attended the hospital without infection and 684 for whom Lyme serology testing was specifically requested as part of a differential diagnosis. In the latter group, the presence or absence of an occupational risk factor was recorded.ResultsAntibodies against B. burgdorferi were detected in 189 individuals (13.2%): 16 (5.1%) in the blood donors group, 62 (14.4%) in subjects who attended hospital without infection and 111 (16.2%) in subjects in whom a differential diagnosis of Lyme disease was requested (p < 0.0001). In subjects with an occupational risk factor, the prevalence was 23.5%, peaking at 45.8% in men over 65 years.ConclusionOur study showed a high prevalence of antibodies against B. burgdorferi and higher than that seen in other areas with similar characteristics in Spain. However, our results are similar to those published from other European regions. The prevalence in the blood donors group was lower than that observed in the other groups. Older age, the male gender and occupational risks were associated with a higher prevalence of Lyme disease. |
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| Keywords: | Seroprevalence Lyme disease |
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