Onyx胶栓塞颅内动静脉畸形的临床分析

目的 探讨Onyx胶栓塞颅内动静脉畸形的临床效果。方法 回顾性分析2008年1月至2014年12月采用Onyx胶栓塞治疗的120例颅内动静脉畸形患者的临床资料。结果 栓塞范围≥80% 56例（畸形团完全闭塞14例），<80% 64例。术中少量出血2例，术后无神经功能缺损。术后出血4例，其中2例死亡。术后一过性神经功能缺损2例。118例随访2~48个月，平均（25.1±5.6）个月，患者头痛、头晕及癫痫等均得到不同程度改善；其中45例DSA随访示，完全闭塞26例，与术前比较无变化19例。结论 Onyx胶血管内栓塞治疗脑动静脉畸形具有良好的效果，但是应掌握其适应症和使用方法。

Endovascular embolization of cerebral arteriovenous malformations with Onyx glue

Objective To explore the clinical effect of endovascular embolization with Onyx glue on intracranial arteriovenous malformations (AVMs). Methods The clinical data of 120 patients with intracranial AVMs, which were endovascularly embolized with Onyx glue from January, 2008 to December, 2014 in our hospital, were analyzed retrospectively. Results The AVMs were embolized over 80% in 56 patients (46.7%) including 14 patients (25.0%, 14/56) receiving complete embolization of AVMs and AVMs were embolized under 80% in 64 patients (53.3%). The intraoperative bleeding occurred in 12 patients without postoperative neurological deficits. The postoperative bleeding occurred in 4 patients, of whom, 2 died and 2 survived. There were temporal neurological deficits after the operation in 2 patients. The symptoms including headache, dizzy, epilepsy and so on were differently improved in degree in 118 patients who were followed up from 2 to 48 months mean, (25.1±5.6) months]. Of 45 patients receiving DSA examination during the following up, 26 had complete occlusion of AVMs and 19 had AVMs about the same before the operation. Conclusions The curative effect of endovascular embolization with Onyx glue on the intracranial AVMs is good, but its indications and method to use it must be mastered well.