2011-2015年南京市第一医院肺部吸入制剂的使用情况分析

目的 分析南京市第一医院肺部吸入制剂的使用情况,为临床合理使用提供参考.方法 对2011—2015年南京市第一医院肺部吸入制剂的种类、用药金额、用药频度(DDDs)、日均药费(DDC)及药品排序比(B/A)等进行统计和分析.结果 2011—2015年肺部吸入制剂的用药金额均呈上升趋势,但占总用药金额的构成比基本稳定.其中用药金额前3位的肺部吸入制剂为吸入用布地奈德混悬液、沙美特罗替卡松粉吸入剂、布地奈德福莫特罗粉吸入剂;DDDs排名前3位的肺部吸入制剂分别为沙美特罗替卡松吸入剂、吸入用布地奈德混悬液、沙丁胺醇气雾剂;沙丁胺醇气雾剂、沙美特罗替卡松吸入剂、噻托溴铵粉吸入剂的B/A较大,而吸入用异丙托溴铵溶液、吸入用布地奈德混悬液的B/A较小,其余吸入制剂的B/A基本接近1.00.DDC排名前3位的肺部吸入制剂分别为吸入用布地奈德混悬液、吸入用异丙托溴铵溶液、布地奈德福莫特罗粉吸入剂.结论 2011—2015年南京市第一医院肺部吸入制剂总体用药和价格结构比较客观合理.

Analysis on usage of pulmonary inhalers in Nanjing First Hospital from 2011 to 2015

Objective To investigate the application of pulmonary inhalers in Nanjing First Hospital, and to provide reference for rational drug use in clinic. Methods The utilization of pulmonary inhalers in Nanjing First Hospital from 2011 to 2015 was analyzed statistically in respects of drug types, consumption sum, DDDs, DDC, and rank ratios of total consumption and DDDs (B/A). Results Consumption sum of pulmonary inhalers had a rising trend from 2011 to 2015, but the proportions of pulmonary inhalers in the total drug use were kept stable. The top 3 drugs of consumption sum were Budesonide Suspension for inhalation, Salmeterol Xinafoate and Fluticasone Propionate Powder for inhalation, and Budesonide and Formoterol Fumarate Powder for inhalation. The top 3 drugs of DDDs were Salmeterol and Fluticasone Propionate for inhalation, Budesonide Suspension for inhalation, and Salbutamol Sulphate Aerosol. B/A values of Salbutamol Sulphate Aerosol, Salmeterol and Fluticasone Propionate for inhalation, and Tiotropium Bromide Powder for inhalation wwere high, while B/A values of Ipratropium Bromide Solution for inhalation and Budesonide Suspension for inhalation were low, and others were near 1.00. The top 3 drugs of DDC were Budesonide Suspension for inhalation, Ipratropium Bromide Solution for inhalation, and Budesonide and Formoterol Fumarate Powder for inhalation. Conclusion The overall drug use and the price structures in Nanjing First Hospital from 2011 to 2015 are reasonable.