脑血康胶囊联合脑苷肌肽注射液治疗高血压脑出血的疗效观察

目的观察脑血康胶囊联合脑苷肌肽注射液治疗高血压脑出血的临床疗效。方法选取2015年7月—2016年6月在澄迈县人民医院就诊的高血压脑出血患者86例,随机分为对照组和治疗组,每组各43例。对照组于术后第1天静脉滴注脑苷肌肽注射液,10 m L稀释于生理盐水250 m L中,1次/d。治疗组在对照组的基础上口服脑血康胶囊,1粒/次,3次/d。两组患者均治疗28 d。评价两组临床疗效,同时比较两组患者治疗前后神经功能缺损评分(NIHSS)和生活质量评分(ADL)评分。结果治疗后,对照组和治疗组的总有效率分别为72.09%、90.70%,两组比较差异有统计学意义(P0.05)。治疗后,两组患者NIHSS评分显著降低,ADL评分显著升高,同组治疗前后比较差异具有统计学意义(P0.05);且治疗组患者NIHSS和ADL评分显著优于对照组患者,两组比较差异具有统计学意义(P0.05)。结论脑血康胶囊联合脑苷肌肽注射液治疗高血压脑出血临床疗效确切,神经功能及生活能力改善明显,具有一定的临床推广应用价值。

Clinical observation of Naoxuekang Capsules combined with Cattle Encephalon Glycoside and Ignotin Injection in treatment of hypertensive cerebral hemorrhage

Objective To observe the clinical effect of Naoxuekang Capsules combined with Cattle Encephalon Glycoside and Ignotin Injection in treatment of hypertensive cerebral hemorrhage. Methods Patients (86 cases) with hypertensive cerebral hemorrhage in Chengmai County People''s Hospital from July 2015 to June 2016 were randomly divided into control and treatment groups, and each group had 43 cases. Patients in the control group were iv administered with Cattle Encephalon Glycoside and Ignotin Injection, 10 mL diluted into normal saline 250 mL, once daily. Patients in the treatment group were po administered with Naoxuekang Capsules on the basis of the control group, 1 grain/time, three times daily. Patients in two groups were treated for 28 d. After treatment, the clinical efficacy was evaluated, and the NIHSS and ADL scores in two groups before and after treatment were compared. Results After treatment, the clinical efficacies in the control and treatment groups were 72.09% and 90.70%, respectively, and there was difference between two groups (P < 0.05). After treatment, the NIHSS scores in two groups were significantly decreased, but the ADL score was significantly increased, and the difference was statistically significant in the same group (P < 0.05). The NIHSS and ADL scores in the treatment group were significantly better than those in the control group, with significant difference between two groups (P < 0.05). Conclusion Naoxuekang Capsules combined with Cattle Encephalon Glycoside and Ignotin Injection have definite clinical efficacy in treatment of hypertensive cerebral hemorrhage, and can significantly improve neurological function and life ability, which has a certain clinical application value.