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Cytogenetic analyses of three papillary carcinomas and a follicular adenoma of the thyroid
Authors:E Olah  E Balogh  F Bojan  F Juhasz  V Stenszky  N R Farid
Affiliation:Department of Pediatrics, Medical University, Debrecen, Hungary.
Abstract:Cytogenetic data of three papillary carcinomas and a follicular adenoma using direct preparations or cell cultures or both after 7 to 60 days in vitro are presented. Although karyotype of the follicular adenoma proved completely normal, in each of the three papillary carcinomas a modal chromosome number in the diploid range and a deleted 11q were observed. In case 1 the del(11)(q23) was associated with rearrangement of chromosome 1 and other marker chromosomes. Our results suggest that 11q deletion may be specific for papillary carcinoma of the thyroid.
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