Cytogenetic analyses of three papillary carcinomas and a follicular adenoma of the thyroid |
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Authors: | E Olah E Balogh F Bojan F Juhasz V Stenszky N R Farid |
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Affiliation: | Department of Pediatrics, Medical University, Debrecen, Hungary. |
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Abstract: | Cytogenetic data of three papillary carcinomas and a follicular adenoma using direct preparations or cell cultures or both after 7 to 60 days in vitro are presented. Although karyotype of the follicular adenoma proved completely normal, in each of the three papillary carcinomas a modal chromosome number in the diploid range and a deleted 11q were observed. In case 1 the del(11)(q23) was associated with rearrangement of chromosome 1 and other marker chromosomes. Our results suggest that 11q deletion may be specific for papillary carcinoma of the thyroid. |
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