Initiation and Discontinuation of Hormone Therapy for Menopausal Symptoms: Results From a Community Sample |
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| Authors: | Hayden B. Bosworth Steven C. Grambow Colleen M. McBride Celette Sugg Skinner Laura Fish Barbara K. Rimer Ilene C. Siegler |
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| Affiliation: | (1) Center for Health Services Research in Primary Care, Durham VAMC, Durham, North Carolina;(2) Department of Medicine, Division of General Internal Medicine, Duke University Medical Center, Durham, North Carolina;(3) Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina;(4) Center for Aging and Human Development, Duke University, Durham, North Carolina;(5) Department of Biostatistics and Bioinformatics, Duke University Medical Center, Durham, North Carolina;(6) Cancer Prevention, Detection, and Control Research Program, Duke Comprehensive Cancer Center, Durham, North Carolina;(7) Department of Community and Family Medicine, Duke University Medical Center, Durham, North Carolina;(8) 8Department of Health Behavior and Health Education, School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina |
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| Abstract: | Factors related to initiation and discontinuation of hormonal therapy (HT) for treatment of menopausal symptoms were examined in a community sample of 533 peri/postmenopausal women aged 45–54 by telephone three times. Over 40 variables including: sociodemographic characteristics, clinical reasons to start HT use, HT contraindications, HT attitudes/knowledge, and health behaviors were examined in logistic regression models comparing women who discontinued HT to women who continued using HT over 9 months (discontinuers) and women who initiated HT versus women who never used HT over 9 months (initiators). Increased understanding of HT, confidence, mental health symptoms, perception that menopause is natural, and having gynecological surgery were related to decreased likelihood of HT discontinuation. Increased understanding about risks of HT, vasomotor symptoms, mood symptoms, and having gynecological surgery were related to increased likelihood of HT Initiation. These findings highlight the importance of physicians discussing HT with their patients, particularly because of recent clinical trial developments. |
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| Keywords: | menopause hormonal replacement medication patient– physician communication adherence climacteric symptoms |
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