新型冠状病毒肺炎CT表现及动态变化

目的 JP2]观察新型冠状病毒肺炎（COVID-19）CT表现及其动态变化。方法 回顾性分析45例经病毒核酸检测确诊、且具有完整动态胸部HRCT资料的COVID-19患者，复查间隔时间48~72 h。结果 29例于发病3天内接受CT检查，21例（21/29，72.41%）胸部见磨玻璃密度影，8例（8/29，27.59%）见磨玻璃密度影伴局部实变，其中2例（25.00%，2/8）为单发结节；26例（26/29，89.66%）病灶呈不规则形或扇形，3例呈类圆形（3/29，10.34%）。16例于发病3天以上接受CT检查，病灶进展。首次复查CT病变均有变化，其中14例（14/45，31.11%）呈单纯磨玻璃密度影，27例（27/45，60.00%）以磨玻璃样密度影为主且有肺实变，4例（4/45，8.89%）以肺实变为主。38例于发病7~10天接受第2次复查，25例（25/38，65.79%）病变范围缩小，4例病灶范围增大（4/38，10.53%），1例（1/38，2.63%）病灶范围同前；8例（8/38，21.05%）原有病灶密度减低但出现新发病灶。其余7例因病变进展而未能接受复查。结论 胸部HRCT能清晰显示COVID-19疾病过程中的影像学变化，有助于指导临床早诊断、早隔离、早治疗，并可作为评价COVID-19临床综合治疗效果的依据。

CT manifestations and dynamic changes of corona virus disease 2019

Objective To explore CT manifestations and dynamic changes of corona virus disease 2019 (COVID-19). Methods Totally 45 COVID-19 patients confirmed by virus nucleic acid detection were collected. All patients had complete dynamic chest HRCT imaging data. The interval of re-examination was 48-72 h. Results Among 29 patients who underwent chest HRCT within 3 days after onset, pure ground glass opacities were found in 21 cases (21/29, 72.41%), while ground glass opacities and consolidation in 8 cases (8/29, 27.59%), including single nodular in 2 cases (2/8, 25.00%). The shape of lesions were irregular or fan-shaped in 26 cases (26/29, 89.66%), while quasi-circular in 3 cases (3/29, 10.34%). The remaining 16 patients had developed more than 3 days before first chest HRCT, all had changes in the first re-examination, including 14 cases (14/45, 31.11%) with pure ground glass opacities and 27 (27/45, 60.00%) with ground glass density and consolidation, while consolidation became dominant in 4 cases (4/45, 8.89%). About 7-10 days after onset, 38 patients underwent the second time re-examination of HRCT, the lesion scope reduced in 25 cases (25/38, 65.79%) but enlarged in 4 cases (4/38, 10.53%), the lesion range remained the same like before in 1 case (1/38, 2.63%), and the lesion''s density decreased with new focus in 8 cases (8/38, 21.05%).The rest 7 patients developed into critical stage and did not have the conditions for HRCT re-examination. Conclusion HRCT can clearly show imaging changes of the whole disease process of COVID-19, which is helpful to guiding early clinical diagnosis, early treatment and early isolation, also providing evidences for evaluating the effect of comprehensive treatment of COVID-19.