MRI评价胎儿胼胝体缺如及其合并畸形

目的 利用MRI评价胎儿胼胝体缺如及其合并畸形。方法 对81胎MRI诊断胼胝体缺如胎儿，分析胼胝体缺如类型，观察其合并颅脑畸形类型及数目。结果 81胎中，单纯胼胝体缺如47胎、合并畸形34胎；合并蛛网膜囊肿12胎，Dandy-Walker畸形7胎，小脑发育不良5胎，神经元移行异常5胎，大枕大池4胎，室管膜下囊肿4胎，脑实质出血2胎，脑裂畸形、脑穿通畸形及脑膜膨出各1胎。结论 MRI可显示胼胝体缺如胎儿及其合并其他颅脑畸形，为评估胎儿预后提供更多信息。

MRI evaluation of fetal corpus callosum agenesis and associated malformations

Objective To evaluate fetal corpus callosum and associated malformations with MRI. Methods Totally 81 fetuses with MRI diagnosed corpus callosum agenesis were collected, and the types and of corpus callosum agenesis and other brain malformations were analyzed. Results Among 81 fetuses, simple absence of corpus callosum were diagnosed in 47 fetuses, while complicated malformations were detected in 34 fetuses, including 12 with arachnoid cyst, 7 with Dandy-Walker syndrome, 5 with cerebellar hypoplasia, 5 with neuronal migration disorder,4 with cisterna magna, 4 with subependymal cyst, 2 with parenchymal hemorrhage, 1 with schizencephaly, 1 with porencephaly and 1 with meningocele. Conclusion MRI can display fetal corpus callosum and associated brain malformations, which is able to provide information for evaluation on prognosis.